- Lower Levels of Vitamin D Are Associated with Higher Vasoactive–Inotropic Scores in Major Cardiac Surgery
- VitaminDWiki – Large dose Vitamin D before surgery was found to help by 35 studies
- VitaminDWiki – Cardiac Surgery with low vitamin D increased delirium 1.4X, mortality 1.5X – May 2020
- VitaminDWiki – Trauma and surgery category contains:
- VitaminDWiki -
16 studies in both categories Cardiovascular and Trauma-Surgery
Lower Levels of Vitamin D Are Associated with Higher Vasoactive–Inotropic Scores in Major Cardiac Surgery
Life 2024, 14(11), 1349; https://doi.org/10.3390/life14111349
by Adrian Stef 1,2ORCID,Constantin Bodolea 2ORCID,Simona Sorana Cainap 3,Monica Muntean 4ORCID,Aurelia Georgeta Solomonean 1,Nadina Tintiuc 1,Razvan Olimpiu Mada 5 and Gabriel Cismaru 6,*Background: The vasoactive–inotropic score (VIS) predicts unfavorable outcomes after cardiac surgery in both children and adults. In our adult population, we investigated whether preoperative levels of vitamin D can predict the VIS and whether both vitamin D and the VIS can predict adverse outcomes following major heart surgery.
Methods: Between 1 October 2021 and 28 February 2022, 300 patients underwent major cardiac surgery at our institution. Eighty-three of them had their 25-OH vitamin D levels measured before surgery. For this cohort, we calculated the VIS based on doses of vasoactive and inotropic medications administered post-surgery. Utilizing receiver operating curves, the predictive accuracy of vitamin D levels and the VIS in predicting acute kidney injury was assessed.
Results: The median age of the cohort was 66 (IQR 61–71) years, with 59% being male and a median BMI of 28.4 (IQR 25.2–31.6). The most common procedures were aortic valve replacement, mitral valve replacement, coronary artery bypass grafting, aortic valve and ascending aorta repair, and ASD correction. There was a significant difference in the postoperative VIS between patients with vitamin D deficiency, i.e., <20 ng/mL, and patients with vitamin D values > 20 ng/mL (3.5 vs. 1.3 p < 0.04). We also found a significant correlation between the VIS and the days of hospitalization (r = 0.335; p = 0.002), the days of stay in the intensive care unit (r = 0.547; p < 0.00001), and the mechanical ventilation time (r = 0.327; p = 0.025). Both vitamin D levels and the VIS predicted postoperative acute kidney injury (p < 0.05).
Conclusions: Vitamin D deficiency is correlated with the VIS in adults undergoing major cardiac surgery. Both vitamin D levels and the VIS can predict unfavorable postoperative outcomes.
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VitaminDWiki – Large dose Vitamin D before surgery was found to help by 35 studies
VitaminDWiki – Cardiac Surgery with low vitamin D increased delirium 1.4X, mortality 1.5X – May 2020
VitaminDWiki – Trauma and surgery category contains:
Trauma and Surgery category has352 articles Large dose Vitamin D before surgery was found to help by 35 studies
Vitamin D is needed before most surgeries – many studies and RCTs
4.8 X more likely to die within 28 days of ICU if low Vitamin D - Jan 2024
Sepsis is both prevented and treated by Vitamin D - many studies
Thyroidectomy and Vitamin D - many studies
Orthopaedic surgeries need Vitamin D – many studies
Cancer - After diagnosis chemotherapy
TBI OR "Traumatic Brain Injury - 21 in title as of Sept 2022
Superbug (Clostridium difficile) Infections strongly associated with low vitamin D - many studies
Glutamine and Omega-3 have also been proven to help several traumas/surgeries
Note: Vitamin D also prevents the need for various surgeries and Omega-3 prevents many concussions/TBI
Trauma and Surgery is associated with 22 other VitaminDWiki categories
Such as loading dose 33, Mortality 23, Infant-Child 21 Intervention 19 Cardiovascular 13, Injection 13 in Sept 2022Did you know?
- You can easily improve outcomes of many planned surgeries by increasing vitamin D ahead of time
- Cancer surgery is the only known exception - extra Vitamin D is OK only if doctor reduces the chemo doses
- A loading dose of Vitamin D also improves unplanned hospital admissions
- Improvements include
- Shorter recovery time
- Shorter ICU time
- Reduced deaths – in hospital, next month, next year
- Reduced Sepsis = blood poisoning = infection
VitaminDWiki -
16 studies in both categories Cardiovascular and Trauma-Surgery This list is automatically updated
- Problems following surgery if low Vitamin D (Cardiac in this case) – Oct 2024
- Afib 40% less likely after heart by-pass if have enough Vitamin D – meta-analysis May 2023
- Surgeries to re-establish blood in brain, heart, etc. are far more successful with high Vitamin D levels – March 2022
- Vitamin D levels dropped 42 percent immediately after pediatric cardiac surgery – Dec 2019
- Getting Vitamin D before heart surgery prevented Afib in those who had been deficient – July 2018
- Heart attack ICU costs cut in half by Vitamin D – Oct 2018
- 3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT March 2018
- Open Heart Surgery associated with low vitamin D, but not if 150,000 IU before surgery – RCT March 2018
- Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis May 2016
- Cardiac rehabilitation had more power if more than 20 nanograms of vitamin D – April 2015
- Congenital Heart problems - vitamin D levels drop even lower after surgery, loading dose probably required - thesis 2015
- Almost 6X more likely to die after coronary bypass if vitamin D deficient – Dec 2012
- Higher vitamin D levels associated with fewer vein clots decades later– Jan 2013
- CV event 56 percent more likely after vascular surgery if low on vitamin D – Oct 2011
- Vitamin D helps organ transplant - many studies
- Bypass surgery and vitamin D – Nov 2010
Problems following surgery if low Vitamin D (Cardiac in this case) – Oct 2024Printer Friendly Follow this page for updates215 visitors, last modified 26 Oct, 2024, This page is in the following categories (# of items in each category) - You can easily improve outcomes of many planned surgeries by increasing vitamin D ahead of time