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Surgeries to re-establish blood in brain, heart, etc. are far more successful with high Vitamin D levels – March 2022

A review on the effects of vitamin D attenuating ischemia reperfusion injuries

INTERNATIONAL JOURNAL OF FOOD PROPERTIES 2022, VOL. 25, NO. 1, 522-540 https://doi.org/10.1080/10942912.2022.2052084
Chaoran Chen a, Xiao Wan a*, Jia Shangb, Wunong Zhangc, and Zhenxing Xied
a institute of Nursing and Health, College of Nursing and Health, Henan University, Kaifeng, HN, China;
b Arts department, School of Kaifeng Culture and Tourism, Kaifeng, HN, China;
c College of Educational Sciences, Henan University, Kaifeng, HN, China;
d School of Basic Medical Sciences, Henan University, Kaifeng, HN, China

PDF Table of contents
Ischemia reperfusion (I/R) injuries occurred in many pathological and surgical processes (e.g. thrombolytic therapy, organ transplantation, aortic crossclamping, coronary angioplasty and cardiopulmonary bypass) and harmed multiple organs and tissues. Vitamin D is a well-known sterol hormone and a nutritional ingredient able to promote the deposit of calcium and regulate phosphorus metabolism in the body. In addition, vitamin D has therapeutic effects on some diseases (e.g. cardiovascular disease, diabetes, cancer, neurological diseases, multiple sclerosis and inflammation).

Studies showed that vitamin D3 was closely related with I/R injury occurrences in

  • heart,
  • brain,
  • Spine,
  • liver,
  • kidney, and
  • ovary.

The literature searching was conducted in PubMed, Embase, Cochrane Library, Web of Science, and SCOPUS from inception to 20 September 2021.
Data showed that supplements with vitamin D3 can remarkably attenuate I/R injuries. This paper reviewed recent progresses of vitamin D3 preventing I/R injuries in clinical investigations and animal tests to enlighten future studies.


 Download the PDF from VitaminDWiki

VitaminDWiki pages with ISCHEMIC (mainly stroke) in title (20 as of Oct 2022)

This list is automatically updated

Items found: 20
Title Modified
Elderly vaccinated for COVID were 2X more likely to die of ischemic stroke (2930 vs 1180 deaths)– Nov 2021 22 Nov, 2021
Poor Ischemic stroke outcome (END) 2.6 X worse if low vitamin D – March 2019 26 Nov, 2019
Death after Ischemic Stroke 2.5 X more likely if less than 10 ng of Vitamin D – May 2019 02 May, 2019
Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018 29 Jun, 2018
Ischemic Stroke risk reduced by 2.5 if have good level of vitamin D – meta-analysis Feb 2018 28 Feb, 2018
Vitamin D levels drop after ischemic stroke – Dec 2017 20 Jan, 2018
Ischemic stroke 17 X more likely if low vitamin D – April 2017 13 Jan, 2018
Large vessel Ischemic Stroke 13 X more likely if low vitamin D – Nov 2017 04 Jan, 2018
Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017 27 Oct, 2017
Ischemic stroke and low vitamin D – 3X higher risk of poor outcome, 6 X higher risk of a second stroke, Oct 2017 04 Oct, 2017
Better outcome following Ischemic stroke if injected with 600,000 IU of vitamin D – RCT Feb 2017 01 Aug, 2017
Death within 2 years of surviving an ischemic stroke 10X less likely if high vitamin D – July 2017 01 Aug, 2017
Risk of Ischemic Stroke doubles if take more than 1 gram of Calcium daily for years – May 2017 20 May, 2017
Ischemic Stroke risk best predicted by Vitamin D, including PTH improves the prediction – Feb 2017 02 Mar, 2017
Ischemic stroke 5 times more likely to recur if very low vitamin D – June 2016 28 Jul, 2016
Ischemic Stroke with low vitamin D resulted in larger lesions – May 2015 11 Mar, 2016
Vitamin D associated with 50 percent less ischemic stroke – meta-analysis Aug 2012 12 Jul, 2015
Ischemic Stroke 3X more likely if Vitamin D Receptor gene change (Fok 1) – Jan 2014 29 Dec, 2014
Ischemic stroke 2X more likely if Vitamin D Receptor gene problem – Dec 2014 17 Dec, 2014
Acute ischemic stroke 19 percent more likely if even lower vitamin D – Sept 2013 14 Sep, 2013

Created by admin. Last Modification: Saturday October 8, 2022 01:35:40 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
18593 I-R pathways.jpg admin 08 Oct, 2022 01:21 68.59 Kb 50
18592 I-R ToC.jpg admin 08 Oct, 2022 01:20 16.91 Kb 42
18591 ischemia reperfusion injuries_CompressPdf.pdf PDF 2022 admin 08 Oct, 2022 01:20 664.46 Kb 20