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Diabetes has many bidirectional links with COVID-19 – March 2021

World J Diabetes. 2021 Mar 15;12(3):215-237. doi: 10.4239/wjd.v12.i3.215.
Vijay Viswanathan 1, Anudeep Puvvula 2, Ankush D Jamthikar 3, Luca Saba 4, Amer M Johri 5, Vasilios Kotsis 6, Narendra N Khanna 7, Surinder K Dhanjil 8, Misha Majhail 9, Durga Prasanna Misra 10, Vikas Agarwal 11, George D Kitas 12, Aditya M Sharma 13, Raghu Kolluri 14, Subbaram Naidu 15, Jasjit S Suri 16 jasjit.suri at atheropoint.com


VitaminDWiki Items in both categories Diabetes and Virus:

Overview Diabetes and vitamin D contains the following

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 480 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

  • Appears that >2,000 IU will Prevent
  • Appears that >4,000 IU will Treat , but not cure
  • Appears that Calcium and Magnesium are needed for both Prevention and Treatment
    • which are just some of the vitamin D cofactors

Number of articles in both categories of Diabetes and:

  • Dark Skin 23;   Intervention 52;   Meta-analysis 34;   Obesity 28;  Pregnancy 40;   T1 (child) 37;  Omega-3 11;  Vitamin D Receptor 21;  Genetics 11;  Magnesium 19    Click here to see details

COVID-19 treated by Vitamin D - studies, reports, videos

As of Oct 20, 2021, the page had:  34 trials 6 trial results,   27 meta-analyses and reviews,   64 observations,   35 recommendations,   55 associations,  89 speculations,  48 videos   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   26 risk factors are ALL associated with low Vit D,   Recent Virus pages   Fight COVID-19 with 50K Vit D weekly   Vaccines

26 health factors increase the risk of COVID-19 – all are associated with low vitamin D

CDC: Confirms Low Vitamin D
VitaminDWiki and other
Cancer VitaminDWiki 7X
Chronic kidney diseaseVitaminDWiki
COPD & other lung problemsPneumonia - VDW
Lung Death 4X
Down Syndrome VitaminDWiki - deficiency
Heart conditionsVitaminDWiki
Immunocompromised stateVitamin D helps organ transplant
Cancer - After diagnosis
Obesity Overview Obesity and Vitamin D
PregnancyOverview Pregnancy and vitamin D
Sickle cell diseaseOverview Sickle Cell and Vitamin D
Smoking Smoking reduces vitamin D
Diabetes T2VitaminDWiki
CDC: Might be factors
Asthma Overview Asthma and Vitamin D
Cerebrovascular disease Cardiovascular   Stroke
Cystic fibrosisCystic Fibrosis
Hypertension VitaminDWiki
ACE inhibitors VitaminDWiki 4X
Neurologic conditions,
such as dementia
Alzheimers-Cognition - Overview
Liver diseaseOverview Liver and vitamin D
Pulmonary fibrosisPulmonary Fibrosis
Thalassemia VitaminDWiki - deficiency
Diabetes T1 T1 Diabetes
CDC: Still fails to mention
AgeOverview Seniors and Vitamin D
Nursing HomeWikipedia
SmokingSmoking JAMA Jan 2021 - 2 x
Smoking reduces vitamin D
Dark SkinVitaminDWiki
Vertebral Fracture VitaminDWiki
Shift workVitaminDWiki 2X
Mood disorders Note:
Low D ==> depression
1.5X increase in COVID-19 death
Concealing clothingVitaminDWiki 3.5X
Schizophrenia 3X mortality VitaminDWiki Low D since birth

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Sometimes A health problem will cause a Vitamin D deficiency
Sometimes A Vitamin D deficiency will cause another health problem
AlwaysStop a vitamin D deficiency to avoid getting additional health problems

This concept and study is discussed at Grassroots Health March 29. 2021

 Download the PDF from VitaminDWiki

Coronavirus disease 2019 (COVID-19) is a global pandemic where several comorbidities have been shown to have a significant effect on mortality. Patients with diabetes mellitus (DM) have a higher mortality rate than non-DM patients if they get COVID-19. Recent studies have indicated that patients with a history of diabetes can increase the risk of severe acute respiratory syndrome coronavirus 2 infection. Additionally, patients without any history of diabetes can acquire new-onset DM when infected with COVID-19. Thus, there is a need to explore the bidirectional link between these two conditions, confirming the vicious loop between "DM/COVID-19".
This narrative review presents

  • (1) the bidirectional association between the DM and COVID-19,
  • (2) the manifestations of the DM/COVID-19 loop leading to cardiovascular disease,
  • (3) an understanding of primary and secondary factors that influence mortality due to the DM/COVID-19 loop,
  • (4) the role of vitamin-D in DM patients during COVID-19, and finally,
  • (5) the monitoring tools for tracking atherosclerosis burden in DM patients during COVID-19 and "COVID-triggered DM" patients.

We conclude that the bidirectional nature of DM/COVID-19 causes acceleration towards cardiovascular events. Due to this alarming condition, early monitoring of atherosclerotic burden is required in "Diabetes patients during COVID-19" or "new-onset Diabetes triggered by COVID-19 in Non-Diabetes patients".

Created by admin. Last Modification: Tuesday March 30, 2021 17:48:56 GMT-0000 by admin. (Version 7)

Attached files

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15348 bidirectional 2.jpg admin 30 Mar, 2021 17:20 212.54 Kb 86
15347 bidirectional links.jpg admin 30 Mar, 2021 17:20 223.24 Kb 105
15346 Bidirectional_link_between_diabetes_mellitus_and_c_compressed.pdf PDF 2021 admin 30 Mar, 2021 17:19 626.84 Kb 66
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