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Aspartame while pregnant increased risk by 3.4 X that male infant will be Autistic – Sept 2023


Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study

Nutrients 2023, 15(17), 3772; https://doi.org/10.3390/nu15173772
by Sharon Parten Fowler 1,*,David Gimeno Ruiz de Porras 2,3,4ORCID,Michael D. Swartz 5,Paula Stigler Granados 6ORCID,Lynne Parsons Heilbrun 7 and Raymond F. Palmer 8

Since its introduction, aspartame—the leading sweetener in U.S. diet sodas (DS)—has been reported to cause neurological problems in some users. In prospective studies, the offspring of mothers who consumed diet sodas/beverages (DSB) daily during pregnancy experienced increased health problems. We hypothesized that gestational/early-life exposure to ≥1 DS/day (DSearly) or equivalent aspartame (ASPearly: ≥177 mg/day) increases autism risk. The case-control Autism Tooth Fairy Study obtained retrospective dietary recalls for DSB and aspartame consumption during pregnancy/breastfeeding from the mothers of 235 offspring with autism spectrum disorder (ASD: cases) and 121 neurotypically developing offspring (controls). The exposure odds ratios (ORs) for DSearly and ASPearly were computed for autism, ASD, and the non-regressive conditions of each.
Among males, the DSearly odds were tripled for autism (OR = 3.1; 95% CI: 1.02, 9.7) and non-regressive autism (OR = 3.5; 95% CI: 1.1, 11.1); the ASPearly odds were even higher: OR = 3.4 (95% CI: 1.1, 10.4) and 3.7 (95% CI: 1.2, 11.8), respectively (p < 0.05 for each). The ORs for non-regressive ASD in males were almost tripled but were not statistically significant: DSearly OR = 2.7 (95% CI: 0.9, 8.4); ASPearly OR = 2.9 (95% CI: 0.9, 8.8). No statistically significant associations were found in females. Our findings contribute to the growing literature raising concerns about potential offspring harm from maternal DSB/aspartame intake in pregnancy.
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  • "Researchers found even one diet soda a day during pregnancy tripled the risk of autism in male offspring."

VitaminDWiki – Autism category contains:

Autism category has 155 items

 - see also Overview Autism and vitamin D,  Autoimmune ,   Cognitive,    ADHD
Interesting Autistic studies
Autism associated with low Vitamin D

Autism treated by Vitamin D

Autism reduced by vitamins before and during pregnancy

Autism and Vitamin D Receptor (not enough Vit D gets to the cells)
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Autism - other risk factors

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Dr. Cannell on Autism and Vitamin D in VitaminDWiki

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See also: Overview Alcohol and Vitamin D

Approximately 3X increase in still birth if drink alcohol while pregnant
Alcohol also increases Premature birth, Birth defects. Fetal alcohol spectrum disorders, and Miscarriage.


See also: Off topic – Proven again – artificial sweeteners actually make you GAIN weight – Oct 2012

Attached files

ID Name Comment Uploaded Size Downloads
20075 Diet soda autism_CompressPdf.pdf admin 06 Sep, 2023 343.05 Kb 57