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Concise summary of 10 Vitamin D and COVID-19 observations - Oct 27, 2020

Daily Mall summary Oct 27

When? September.

By who? Cordoba University in Spain.

What did scientists study? 50 Covid-19 hospital patients with Covid-19 were given vitamin D. Their health outcomes were compared with 26 volunteers in a control group who were not given the tablets.

What did they find? Only one of the 50 patients needed intensive care and none died. Half of 26 virus sufferers who did not take vitamin D were later admitted to intensive care and two died.

What were the study's limitations? Small pool of volunteers. Patients' vitamin D levels were not checked before admission. Comorbidities were not taken into consideration.

When? September.

By Who? University of Chicago.

What did scientists study? 500 Americans' vitamin D levels were tested. Researchers then compared volunteers' levels with how many caught coronavirus.

What did they find? 60 per cent higher rates of Covid-19 among people with low levels of the 'sunshine vitamin'.

What were the study's limitations?  

Researchers did not check for other compounding factors. Unclear whether or not volunteers were vitamin D deficient at the time of their coronavirus tests. People's age, job and where they lived - factors which greatly increase the chance of contracting the virus - were not considered.

When? September.

By Who? Tehran University, in Iran, and Boston University.

What did scientists study? Analysed data from 235 hospitalized patients with Covid-19.

What did they find? Patients who had sufficient vitamin D - of at least 30 ng/mL— were 51.5 per cent less likely to die from the disease. They also had a significantly lower risk of falling seriously ill or needing ventilation. Patients who had plenty of the nutrient also had less inflammation - often a deadly side effect of Covid-19. 

What were the study's limitations? Confounding factors, such as smoking, and social economic status were not recorded for all patients and could have an impact on illness severity.  

When? July.

By Who? Tel Aviv University, Israel.

What did scientists study? 782 people who tested positive for coronavirus had their vitamin d levels prior to infection assessed retrospectively and compared to healthy people.

What did they find? People with vitamin D levels below 30 ng/ml - optimal - were 45 per cent more likely to test positive and 95 per cent more likely to be hospitalised.

What were the study's limitations?  Did not look at underlying health conditions and did not check vitamin D levels at the time of infection.

When? June.

By Who? Brussels Free University.

What did scientists study? Compared vitamin D levels in almost 200 Covid-19 hospital patients with a control group of more than 2,000 healthy people.

What did they find? Men who were hospitalised with the infection were significantly more likely to have a vitamin D deficiency than healthy men of the same age. Deficiency rates were 67 per cent in the COVID-19 patient group, and 49 per cent in the control group. The same was not found for women.

What were the study's limitations?  Independent scientists say blood vitamin D levels go down when people develop serious illness, which the study did not take into consideration. This suggests that it is the illness that is leading to lower blood vitamin D levels in this study, and not the other way around.

When? June.

By who? Inha University in Incheon, South Korea.

What did scientists study? 50 hospital patients with Covid-19 were checked for levels of all vital vitamins and compared to a control group.

What did they find? 76 per cent of them were deficient in vitamin D, and a severe vitamin D deficiency (<10 ng/dl) was found in 24 per cent of Covid-19 patients and just 7 per cent in the control group.

What were the study's limitations?  

Small sample size and researchers never accounted for vitamin levels dropping when they fall ill.

When? June.

By Who?. Independent scientists in Indonesia.

What did scientists study? Checked vitamin D levels in 780 Covid-19 hospital patients.

What did they find? Almost 99% of patients who died had vitamin D deficiency. Of patients with vitamin D levels higher than 30 ng/ml  - considered optimal - only  per cent died.

What were the study's limitations?  It was not peer-reviewed by fellow scientists, a process that often uncovers flaws in studies.

When? May.

By Who? University of Glasgow.

What did scientists study? Vitamin D levels in 449 people from the UK Biobank who had confirmed Covid-19 infection. 

What did they find? Vitamin D deficiency was associated with an increased risk in infection - but not after adjustment for con-founders such as ethnicity. It led to the team to conclude their 'findings do not support a potential link between vitamin D concentrations and risk of Covid-19 infection.'

What were the study's limitations?  Vitamin D levels were taken 10 to 14 years beforehand. 

When? May.

By Who? University of East Anglia.

What did scientists study? Average levels of vitamin D in populations of 20 European countries were compared with Covid-19 infection and death rates at the time.

What did they find? The mean level of vitamin D in each country was 'strongly associated' with higher levels of Covid-19 cases and deaths. The authors said at the time: 'The most vulnerable group of population for Covid-19 is also the one that has the most deficit in vitamin D.'

What were the study's limitations?  The number of cases in each country was affected by the number of tests performed, as well as the different measures taken by each country to prevent the spread of infection. And it only looked at correlation, not causation.

When? May.

By Who? Northwestern University.

What did scientists study? Crunched data from dozens of studies around the world that included vitamin D levels among Covid-19 patients. 

What did they find? Patients with a severe deficiency are twice as likely to experience major complications and die.

What were the study's limitations?  Cases and deaths in each country was affected by the number of tests performed.


COVID-19 treated by Vitamin D - studies, reports, videos

As of Jan 26 had:  34 trials4 trial results,  13 meta-analyses and reviews,   46 observations,   27 recommendations,   42 associations,  84 speculations,  38 videos   see also COVID-19 and Vitamin D:   Governments.   Health problems.   Hospitals

Top Vitamin D and COVID-19 recent updates

Many clinical trials are underway which are testing Vitamin D to fight COVID-19

COVID-19 RCTs


50 most-recently changed items in Virus Category in VitaminDWiki

Id Page Hits Last modification Creator Categories
12264 Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) – Jan 25, 2021 169
27 Jan, 2021 18:32
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11728 COVID-19 treated by Vitamin D - studies, reports, videos 26502
26 Jan, 2021 17:52
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12263 Vitamin D plus Inositol might help pregnancies during COVID-19 – April 2021 46
26 Jan, 2021 14:31
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12262 Vitamin D supplementation fights COVID-19 – 11th meta-analysis Jan 24, 2021 116
26 Jan, 2021 14:03
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12261 MATH plus protocol for COVID-19 includes Calcifediol or Vitamin D - Jan 2021 71
26 Jan, 2021 10:19
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12259 Intermectin and COVID-19 127
26 Jan, 2021 07:19
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12258 Vitamin D helps the immune system fight COVID-19 – video Jan 21, 2021 106
26 Jan, 2021 03:08
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12255 COVID-19 2.7 X more likely to be severe if less than 30 ng of vitamin D (China) – Jan 2021 95
24 Jan, 2021 19:45
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12254 2.7 fewer COVID-19 hospital deaths in those having more than 30 ng of vitamin D – Mayo Jan 9, 2021 164
24 Jan, 2021 19:44
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12235 Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021 220
24 Jan, 2021 19:43
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12250 Vitamin D Help Us Fight Infections - interview of Dr. Thakkar (transcript) Jan 20, 2021 109
24 Jan, 2021 03:39
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9072 Flu 12615
23 Jan, 2021 17:00
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12253 COVID-19 onset strongly associated with latitude in Europe (Vitamin D)– Jan 21, 2021 168
23 Jan, 2021 16:17
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12232 400,000 COVID deaths, 400,000 IUs of Vitamin D needed to prevent COVID death - Jan 2021 177
22 Jan, 2021 15:08
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11919 Acute viral respiratory infections reduced by Vitamin D - overview of 20 reviews - Aug 2020 429
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12245 1170 vaccinations to prevent 1 severe COVID-19 case , vs 1.2 vaccinations to prevent 1 case of Measles 93
22 Jan, 2021 00:33
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12238 Vitamin D, COVID - Campbell and Davis (UK with transcript) - Jan 18, 2021 296
20 Jan, 2021 20:07
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12161 Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination 567
20 Jan, 2021 18:38
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12223 Herd immunity occurs only via vaccination - W.H.O. Oct 2020 72
20 Jan, 2021 13:50
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12229 Many COVID-19 risks are associated with low vitamin D (7 studies) – Systematic Review Jan 2021 137
20 Jan, 2021 13:50
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12239 War increases risks of COVID-19 (social distance, mask, less sun, poor food, stress) - Jan 2021 63
20 Jan, 2021 13:48
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12242 1 in 8 Recovered COVID-19 Patients Die Within 5 Months - Jan 18, 2021 74
20 Jan, 2021 12:56
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11925 Long term fatigue, etc. common after viral infections (SARS1,2, MERS, Swine, 1918,...) 584
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12067 Governments are starting to use vitamin D to fight COVID-19 915
20 Jan, 2021 12:31
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12240 Elderly COVID-19 patients getting 400,000 IU of vitamin D had better survival (Italy, April)– Jan 14, 2021 322
19 Jan, 2021 23:59
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12234 .Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021 13
18 Jan, 2021 03:22
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12233 Vitamin D to prevent COVID- strange trial recommendations from the UK – Jan 2021 100
18 Jan, 2021 03:11
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12227 40 ng of Vitamin D to fight COVID 15K to 50K weekly or 100K monthly – Spanish Jan 2021 145
16 Jan, 2021 11:23
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12213 30 x fewer COVID-19 deaths in those getting 400,000 IU of Vitamin D - Jan 2021 552
15 Jan, 2021 16:23
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11959 Admission to COVID-19 ICU 1.7X more likely to have less than 20 ng of vitamin D – Sept 2020 238
15 Jan, 2021 14:07
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12043 COVID-19 survivors can have poor health for a long time 203
14 Jan, 2021 20:40
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12221 Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021 265
13 Jan, 2021 21:04
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12220 4X fewer COVID-19 deaths in those having high Omega-3 index – Jan 6, 2021 108
13 Jan, 2021 20:38
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11703 Coronavirus might hitch a ride on air pollution - March 2020 818
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12219 COVID-19 cases in Delhi increased 7 days after pollution (less UV and Vitamin D, indoors more) Jan 12, 2021 82
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12195 Vitamin D reduces COVID-19 by 80 percent - anonymous meta-analysis - Jan 5, 2021 564
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12216 Many increased risks for dying of COVID-19 in nursing home (Vitamin D not even mentioned) - Jan 6 2021 51
11 Jan, 2021 23:36
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12217 Active vitamin D (calcitriol) might fight COVID-19 – Jan 5, 2021 102
11 Jan, 2021 23:28
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12215 Vitamin D sales up 40 percent in Dec (2020 vs 2019) 126
11 Jan, 2021 20:03
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12210 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021 242
10 Jan, 2021 21:04
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12197 Don’t Let COVID-19 Patients Die With Vitamin D Deficiency - Jan 5, 2021 460
10 Jan, 2021 20:14
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12035 COVID-19 lung death 4X more likely in Iran if less than 25 ng of vitamin D – Oct 30, 2020 590
10 Jan, 2021 04:29
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Mortality and D
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11945 14.7 X more likely to die of COVID-19 if less than 12 ng of Vitamin D (185 Germans) – Sept 10, 2020 945
10 Jan, 2021 04:28
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11901 COVID ARDS deaths 2X more likely if less than 10 ng of Vitamin D – Aug 8, 2020 564
10 Jan, 2021 04:28
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12010 9X COVID-19 survival in nursing home if had 80,000 IU dose of vitamin D in previous month – Oct 2020 1646
10 Jan, 2021 04:25
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12073 Hospital COVID-19 observation: 7X more likely to live if more than 20 ng of vitamin D– Nov 19, 2020 788
10 Jan, 2021 04:22
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12090 COVID-19 male mortality increased 3.9 X if low vitamin D – observation Nov 25, 2020 195
10 Jan, 2021 04:21
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12145 7X less likely to die of COVID-19 if taking Vitamin D loading dose – Dec 11, 2020 827
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12190 Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020 258
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12207 COVID-19 Disease and Vitamin D: A Mini-Review – Dec 15, 2020 132
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