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Sarcopenia reduction: Protein, Leucine, Omega-3, Vitamin D, and exercise - hypothesis Aug 2018

An Update on Protein, Leucine, Omega-3 Fatty Acids, and Vitamin D in the Prevention and Treatment of Sarcopenia and Functional Decline

Nutrients 2018, 10(8), 1099; https://doi.org/10.3390/nu10081099
Anne-Julie Tessier 1,2 and Stéphanie Chevalier 1,2,3, stephanie.chevalier at mcgill.ca
1 School of Human Nutrition, McGill U., 21111 Lakeshore Rd, Ste-Anne-de-Bellevue, QC H9X 3V9, Canada
2 Research Institute of the McGill U. Health Centre, 1001 Décarie Blvd, Montreal, QC H4A 3J1, Canada
3 Department of Medicine, McGill U., 845 Sherbrooke St. W, Montreal, QC H3A 0G4, Canada
Received: 22 July 2018 / Revised: 9 August 2018 / Accepted: 14 August 2018 / Published: 16 August 2018
(This article belongs to the Special Issue Dietary Intake and Musculoskeletal Health)

VitaminDWiki

This study documents trials using various combinations to succesfully decrease Sarcopenia
Their hypothesis is that using all 5 elements will synergistically treat Sarcopenia


VitaminDWiki pages containing SARCOPENIA in title (16 as of Oct 2021)

This list is automatically updated

Items found: 17
Title Modified
Sarcopenia with obesity is more likely if dark skin, diabetes, OR COPD (all associated with low vitamin D) 16 Oct, 2021
Severe sarcopenia (loss of muscle) 6 X more likely in women with rheumatoid arthritis having low vitamin D – Oct 2021 16 Oct, 2021
Sarcopenia (muscle loss) and Vitamin D 16 Oct, 2021
Loss of muscle strength –sarcopenia – one of the suspects is vitamin D – Aug 2012 16 Oct, 2021
Sarcopenia (muscle loss) is 1.6X more likely if poor Vitamin D receptor – July 2020 23 Jul, 2020
Sarcopenia reduction: Protein, Leucine, Omega-3, Vitamin D, and exercise - hypothesis Aug 2018 30 Jan, 2020
Muscle loss (sarcopenia) may be both prevented and treated by Omega-3 – Feb 2019 23 Feb, 2019
Seniors can restore lost muscle (Sarcopenia) – first restore vitamin D, then exercise – July 2018 13 Jul, 2018
Sarcopenia does not officially exist in Australia, but 1 in 3 of their seniors have it - July 2018 03 Jul, 2018
Sarcopenia: Nutrition and physical activity – systematic review – Jan 2017 10 Mar, 2017
Added 1 lb of muscle to sarcopenia adults in 13 weeks with just 800 IU vitamin D and protein – RCT Jan 2017 31 Jan, 2017
Hypothesis: Sarcopenia and other senior problems are related to low gastic acid 12 May, 2015
Sarcopenia and non-alcoholic fatty liver disease (vitamin D not mentioned) – Sept 2013 07 Mar, 2015
Hypothesis: Sarcopenia and other senior problems are related to low gastric acid 01 Feb, 2015
Vitamin D is one of the treatments for sarcopenia – Nov 2012 31 Jan, 2015
No correlation found between vitamin D and sarcopenia – German dissertation Jan 2013 22 Jan, 2013
Novel treatment approaches to cachexia and sarcopenia: 13 Apr, 2010

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Aging is associated with sarcopenia and functional decline, leading to frailty and disability. As a modifiable risk factor, nutrition may represent a target for preventing or postponing the onset of these geriatric conditions. Among nutrients, high-quality protein, leucine, vitamin D, and omega-3 polyunsaturated fatty acids (n-3 PUFA) are of particular interest for their demonstrated effects on skeletal muscle health. This narrative review aims to examine the recent observational and interventional evidence on the associations and the role of these nutrients in the muscle mass, strength, mobility, and physical function of free-living older adults, who are either healthy or at risk of frailty. Recent evidence supports a higher protein intake recommendation of 1.0–1.2 g/kg/day in healthy older adults; an evenly distributed mealtime protein intake or minimal protein per meal may be beneficial. In addition, vitamin D supplementation of 800–1000 IU, particularly when vitamin D status is low, and doses of ~3 g/day of n-3 PUFA may be favorable for physical function, muscle mass, and strength. Reviewed studies are highly heterogenous, yet the quantity, quality, and timing of intakes should be considered when designing intervention studies. Combined protein, leucine, vitamin D, and n-3 PUFA supplements may convey added benefits and may represent an intervention strategy in the prevention of sarcopenia and functional decline.


Created by admin. Last Modification: Saturday October 16, 2021 15:33:51 GMT-0000 by admin. (Version 10)

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10359 Sarcopenia.jpg admin 16 Aug, 2018 09:03 37.09 Kb 1274
10358 Sarcopenia - protein, leucine, Vit D, Omega-3.pdf PDF 2018 admin 16 Aug, 2018 09:01 616.68 Kb 478
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