Gynecol Endocrinol. 2015 Oct 22:1-22. [Epub ahead of print]
Buggio L1, Roncella E1, Somigliana E1, Vercellini P1.
1a Istituto Ostetrico e Ginecologico 'Luigi Mangiagalli', Department of Clinical Science and Community Health, Università degli Studi, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico , Via Commenda , 12 - 20122 Milano , Italy .
Vitamin D is a fat-soluble pro-hormone that plays an important role in bone homeostasis; beside this principal function, vitamin D promotes modulation of cell growth, neuromuscular and immune function, and reduction of inflammation. In addition, several in vitro and in vivo studies have demonstrated that vitamin D deficiency could increase the risk of cancer, autoimmune and cardiovascular diseases. Moreover, vitamin D plays also an important role in female reproduction, due to the fact that vitamin D receptors are expressed in ovarian tissue, endometrium, fallopian epithelial cells as well as in decidua and placenta. We aimed to review the most updated evidence, which suggests a link between vitamin D metabolism and the development of some gynaecological diseases, such as
- uterine fibroids, and
- polycystic ovary syndrome.
- Overview Women and Vitamin D
- Uterine Fibroids (uterine leiomyoma, need hysterectomy) 1.9 more likely if a Vitamin D receptor problem – Sept 2015
- Search Endometriosis in VitaminDWiki 50 as of OCT 2015
- Search for PCOS 101 as of June 2015
The TOP articles in the category Women are:
- Postmenopausal women need Vitamin D, protein and exercise to prevent loss of muscle and bone – Aug 2018
- Multiple Sclerosis – 3X higher incidence in women, previously 1X, wonder why
- Overweight senior women with low vitamin D were 12X more likely to be weak – Feb 2018
- Vitamin D helps women in many ways – but not sure about ovarian and endometrial cancer – Dec 2016
- Vitamin D for depression and PCOS: killing two birds with one stone (title only - should be 60 birds) – July 2015
- Vitamin D helps women in many ways – review April 2015
- ALL of the top 10 health problems of women are associated with low vitamin D
- 2X increased chance of anemia (low iron) associated with low vitamin D – Sept 2013
- Huge variation in taking vitamin D supplements with age of female, less than 1000 IU not help much – July 2013
- Puberty for girls much earlier if low vitamin D – perhaps for boys as well
- Female Athlete health problems may be due to lack of vitamin D and Iron – July 2012
- Vitamin D - roles in women's reproductive health - Nov 2011