Protein, muscles, bones and Vitamin D - many studies

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25+ VitaminDWiki pages have PROTEIN (with exclusions) in the title

The list is automatically updated

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VitaminDwiki – Muscles and Vitamin D - many studies contains

To build muscles you need more than just Vitamin D
   also need Exercise, Protein, Magnesium, Omega-3, and activated Vitamin D Receptors
     In fact, Vitamin D monotherapy sometimes DECREASES muscles.
Notes on Vitamin D Receptor:
Vitamin D Receptors get vitamin D in the blood to the muscle cells
Approximately 20% of people have poor vitamin D receptors
As people age, their Vitamin D receptors also become less activated
There are 12+ low-cost activators for the Vitamin D Receptor
142+ VitaminDWiki pages have MUSCLE in the title
Dr. Greger on Vitamin D and Muscles - May 2020
Vitamin D Supplements for Increasing Aging Muscle Strength

• "We have known for more than 400 years that muscle weakness is a common presenting symptom of vitamin D deficiency"
• conservative "U.S. Preventive Services Task Force, the official prevention guideline setting body, and the American Geriatric Society to “recommend vitamin D supplementation for persons who are at high risk of falls.”
• AGS recommends 4,000 IU to capture 92 percent of the population"

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VitaminDwiki Sarcopenia (muscle loss) fought by Vitamin D, exercise and protein - many studies contains

To gain muscle, many studies have found that you need some of the following:
Exercise - just even walking (Intermittent high intensity exercise is much better)
Vitamin D - at least 800 IU/day,
    Loading dose will show improvements in weeks instead of 4+ months
Protein - perhaps 1gm/kg/day in a form appropriate for existing stomach acid
Calcium - 300 mg?
Omega-3
Includes the following studies:

• Muscle loss with aging (Sarcopenia) is 7.7 X more likely if Vitamin D deficient – July 2023
• Every trial found Scopenia to be associated with low vitamin D - Meta-analysis 2018
• Sarcopenia 1.6X more likely if you have a poor VDR – Nov 2020

See also Bone Health   reduce falls and fractures   Frailty and Vitamin D - many studies   Muscles and Vitamin D - many studies

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Is there any association between protein and "vitamin d"? - asked Perplexity AI Dec 2024

There is indeed a significant association between protein and vitamin D, particularly in the context of muscle health and function. This relationship has been the subject of numerous studies, revealing several important connections:
Muscle Protein Synthesis
Dietary protein intake, especially when rich in leucine (an amino acid abundant in whey protein), combined with vitamin D, plays a crucial role in muscle protein synthesis 1 2
This combination is particularly important for maintaining and building muscle mass.
Supplementation Effects
Research has shown that combining whey protein and vitamin D supplementation can have beneficial effects on muscle mass and strength:

• A 6-week study on healthy, untrained males found that supplementing with 25g of whey protein and 4000 IU of vitamin D3, either before bedtime or after sleeping, resulted in significant improvements in muscle mass and associated blood hormones compared to a control group  1 2
• Co-supplementation of whey protein and vitamin D has been shown to enhance lean mass gains, muscle strength, and physical function, particularly in healthy older adults 5

Vitamin D Status and Protein Utilization
The relationship between protein and vitamin D extends beyond simple co-supplementation:

• Vitamin D status may influence the efficacy of protein supplementation. Normalizing circulating vitamin D concentrations from deficient or insufficient to replete levels may be critical in determining the effectiveness of protein supplementation  5
• Low vitamin D status is often associated with systemic low-grade inflammation, as reflected by elevated C-reactive protein (CRP) levels  4

This inflammation could potentially impact protein metabolism and muscle health.
Implications for Specific Populations
The protein-vitamin D association appears to have particular relevance for certain groups:

• In older adults, especially those with overweight or obesity, there's often an inadequate intake of both protein and vitamin D 3

This deficiency can contribute to age-related muscle loss and decreased function.

• For sarcopenic or frail older adults, whey protein supplementation alone has shown improvements in lean mass and physical function 5

In conclusion, the association between protein and vitamin D is multifaceted, involving their combined effects on muscle synthesis, strength, and overall function. This relationship is particularly important in the context of aging and muscle health, suggesting that considering both nutrients together may be more beneficial than focusing on either one alone.

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Optimal Protein Intake Guide & Calculator - Examine.com Dec 2024

• "Your optimal daily protein intake depends on your weight, goal, and level of physical activity: from 1.2 g/kg if you’re sedentary all the way up to 2.7 g/kg for serious athletes in certain contexts."