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Kidneys, Vitamin D and Calcium – Oct 2015

Vitamin D and the kidneys: a fascinating relationship – EDITORIAL

J. Bras. Patol. Med. Lab. vol.51 no.5 Rio de Janeiro Sept./Oct. 2015, http://dx.doi.org/10.5935/1676-2444.20150045
José Gilberto Henriques Vieira 1
1Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM/Unifesp)

The complexity of the physiological system that controls serum calcium levels is remarkable. In the Figure we present a very simplified view of this system, stressing the crucial role of vitamin D and the kidneys in the overall complex. No wonder, the system without normal renal function turns out to be highly deranged. Chronic kidney disease (CKD) is, unfortunately, very frequent, and metabolic bone disease, the result of specific alterations in calcium and phosphorus metabolism, one of its main complications(1). The availability of kidney transplantation provided a real step forward in CKD patients' survival and quality of life. For the majority of transplant patients, a return to nearly normal renal function is the more likely result(2).

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Kidneys, Vitamin D and Calcium – Oct 2015

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