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Gut problems associated with low vitamin D – invited review Dec 2015

Vitamin D deficiency in patients with intestinal malabsorption syndromes – think in and outside the gut (invited review)

Journal of Digestive Diseases, Volume 16, Issue 11, pages 617–633, November 2015
Article first published online: 29 DEC 2015, DOI: 10.1111/1751-2980.12283
Samantha L Margulies1, Divya Kurian1, Mark S Elliott2 andZhiyong Han2,*
© 2015 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd

There is a very high prevalence of vitamin D deficiency, which is defined by a serum level of 25-hydroxyvitamin D 25(OH)D of lower than 20 ng/mL, in all populations of the world. Unfortunately, the prevalence of vitamin D deficiency in patients with intestinal malabsorption syndromes, including

  • cystic fibrosis (CF),
  • celiac disease (CD),
  • short bowel syndrome and
  • inflammatory bowel disease (IBD),

is higher than that in the general population, indicating the presence of disease-specific causative factors. In this review, we aimed to present clinical findings to highlight the roles of insufficient exposure to sunlight and inflammation in the development of vitamin D deficiency in patients with intestinal malabsorption syndromes. Furthermore, we aimed to present experimental evidence that supported a role of vitamin D deficiency in the pathogenesis of IBD.

Finally, we reviewed clinical intervention strategies aiming to normalize vitamin D status in and even to improve the conditions of patients and to discuss certain issues that needed to be addressed in future research.

One table from the study

Study was rented for $6 by VitaminDWiki

  • They notice that those with gut problems have poor time getting vitamin D in thru he gut
  • They mention that UV and sublingual might be good ways to get vitamin D
  • Little mention of genes
  • They seem to not mention many other forms such as topical, spray, injection, and gut-friendly

See also VitaminDWiki

The Meta-analysis of Gut and Vitamin D

All items in categories Intervention AND Gut

Many ways to increase Vitamin D
click on chart for details

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