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Bladder infection and Vitamin D - many studies


7+ VitaminDWiki pages containing URINARY TRACT INFECTION or UTI in title

Items found: 8

4+ VitaminDWiki pages with BLADDER in title

This list is automatically updated

Items found: 22
Title Modified
Bladder cancer in muscles 2.7 times more-likely if vitamin D less than 20 ng -meta-analysis May 2024 23 May, 2024
Cancers are sometimes associated with poor CYP24A1 gene (Vitamin D) (Bladder Cancer in this case) – April 2024 23 Apr, 2024
Overactive bladder 4.4 X more likely if low vitamin D – meta-analysis Feb 2024 21 Feb, 2024
Bladder infection and Vitamin D - many studies 17 May, 2023
Cancer - Bladder 23 Jun, 2022
Bladder Cancer deaths – 2.9X more likely if low Vitamin D, no death if more than 30 ng – July 2020 17 Jul, 2020
Overactive bladder 32 X more likely if very low vitamin D – April 2019 29 Dec, 2019
Good Vitamin D receptor reduced bladder cancer and cisplatin deaths – April 2019 11 Apr, 2019
Urgent need to pee (Overactive Bladder) in elderly men was decreased by 200,000 IU Vitamin D injection – May 2018 14 May, 2018
Urinary Bladder Cancer survival is associated with vitamin D receptor: 14 months vs 53 months – Oct 2015 02 Mar, 2017
Bladder cancer modifiable risk factors include low vitamin D – meta-analysis March 2016 08 Dec, 2016
Bladder cancer 60 percent less likely if have high vitamin D – meta-analysis Dec 2015 08 Dec, 2016
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis April 2015 24 Dec, 2015
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis Oct 2014 24 Dec, 2015
Poor Bladder Cancer survival associated with poor Vitamin D receptor – Oct 2015 18 Oct, 2015
80 percent more likely to have bladder cancer if have low level of vitamin D – Oct 2012 02 Nov, 2014
Hypothesis: Vitamin D or UV will decrease bladder cancer – Feb 2013 02 Nov, 2014
Higher levels of Vitamin D assocated with bladder cancer survival by veterans – Feb 2013 02 Nov, 2014
Free vitamin D (VDR) may be more important than total for bladder cancer – March 2013 06 Jan, 2014
Bladder Cancer, Vitamin D, and Fibroblast Growth Factor – Oct 2012 31 Oct, 2012
Less than 20 ng of Vitamin D increases bladder cancer by 70 percent – Oct 2010 31 Oct, 2012
1200 IU of vitamin D did not have any impact on bladder cancer – June 2010 02 Jun, 2010

Serum Vitamin D Level and the Risk of Urinary Tract Infection in Children - March 2021

: A Systematic Review and Meta-Analysis FREE PDF


UTI in children 5.5 X more likely if <20 ng of Vitamin D Meta-analysis May 2023

The Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis FREE PDF


Overactive bladder 4.4X more-likely if low vitamin D - Meta-analysis May 2023

Vitamin D levels and the risk of overactive bladder: a systematic review and meta-analysis
Nutr Rev. 2023 May 17;nuad049. doi: 10.1093/nutrit/nuad049
Qiang Zhang 1 2 3, Zhicheng Zhang 1 2 3, Xueyu He 1 2 3, Zhenmin Liu 1 2 3, Lianju Shen 1 2 3, Chunlan Long 1 2 3, Guanghui Wei 1 2 3, Xing Liu 1 2 3 4, Chunming Guo 5

Context: Overactive bladder is treated mainly with behavioral and drug therapy, and symptoms of urinary frequency and incontinence are challenging to eliminate. There is thus a continuous unmet need for new drugs with a substitution effect mechanism.

Objective: It not known whether vitamin D deficiency can lead to overactive bladder or urinary incontinence or whether vitamin D supplementation alleviates bladder symptoms. This comprehensive systematic review with meta-analysis was conducted to determine whether overactive bladder is associated with vitamin D deficiency.

Data sources: The PubMed and Cochrane Library databases were searched systematically up to July 3, 2022.

Data extraction: Initially, 706 articles were identified in the literature search, of which 13 were included in the systematic review: 4 randomized controlled trials, 3 cohort studies, 3 cross-sectional studies, and 3 case-control studies.

Data analysis: An increased risk of overactive bladder and urinary incontinence was observed with vitamin D deficiency (odds ratio OR = 4.46; 95%CI, 1.03-19.33; P = 0.046 and OR = 1.30; 95%CI, 1.01-1.66; P = 0.036, respectively). Vitamin D levels were relatively low in patients with overactive bladder or urinary incontinence (SMD = -0.33; 95%CI, -0.61 to -0.06, P = 0.019).
On the basis of existing data, the risk of urinary incontinence was reduced by 66% after vitamin D supplementation (OR = 0.34; 95%CI, 0.18-0.66; P = 0.001). Egger test was conducted to assess publication bias, and the results were tested for robustness using a sensitivity analysis.

Conclusions: Vitamin D deficiency increases the risk of overactive bladder and urinary incontinence, and vitamin D supplementation reduces the risk of urinary incontinence. The development of new strategies to prevent or alleviate bladder symptoms is crucial. Vitamin D supplementation may be gaining recognition as an effective strategy for prevention or alleviation of bladder symptoms such as overactive bladder and incontinence.

Systematic review registration: PROSPERO registration no. CRD42022351443.


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  • Vitamin D levels and the risk of overactive bladder: a systematic review and meta-analysis Feb 2024 https://doi.org/10.1093/nutrit/nuad049 PDF behind paywall
  • Overactive bladder and associated psychological symptoms: A possible link to vitamin D and calcium - March
  • The effect of vitamin D deficiency in children with overactive bladder related urinary incontinence - Apr 2022 • FREE PDF
  • The effect of vitamin D deficiency and supplementation on urinary incontinence: scoping review - 2022 FREE PDF
  • Vitamin D intake and the 10-year risk of urgency urinary incontinence in women - May 2020 FREE PDF
  • Vitamin D Intake and Progression of Urinary Incontinence in Women - April 2021 https://doi.org/10.1016/j.urology.2020.04.090 FREE PDF

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