Impacts of Serum 25-OH Vitamin D Level on Lower Urinary Tract Symptoms in Male: A Step Forward to Decrease Overactive Bladder.
BJU Int. 2018 May 9. DOI: 10.1111/bju.14387
Yoo S1, Oh S2, Kim HS3, Choi HS4, Park J1, Cho SY1, Son H1, Jeong H1, Lee HW3, Cho MC1.
Vitamin D levels after injection peaked at 25 ng (need at least 30 ng to fight a health problem)
The improvement in the total OABSS (Oeveractive Bladder Symtom Score) after vitamin D replacement was significantly associated with a lower pre-treatment total OABSS (r=-0.744, p<0.001
Overactive Bladder in Winter*
* Significant association only existed in winter
Injection is typically not necessary – Oral supplementation of 200,000 IU or more Vitamin D within a week would probably work as well
- Recurrent urinary tract infection 4X more likely if low vitamin D – Aug 2013
- Prostate and Urinary systems much better with higher vitamin D – many studies
- Search VitaminDWiki for Urinary Tract Infection 289 items as of May 2018
- Urinary tract infection or bladder infection and vitamin D
- Urinary tract infection rate cut in half by weekly 20,000 IU vitamin D – RCT June 2016
- Urinary tract infection in children strongly associated with low vitamin D – Feb 2015 3.5X
- Urinary Tract Infection in infants: 5.6 X more likely if low Vitamin D, 70 percent less likely if supplement – Judy 2016
- Injection category listing has
40 items along with related searches
To evaluate the impacts of serum vitamin D level on male lower urinary tract symptoms (LUTS).
MATERIALS AND METHODS:
From 2014 to 2017, 434 male patients with LUTS were included. The impacts of vitamin D on LUTS were evaluated using multivariate analysis to adjust for age, body mass index, prostate specific antigen, testosterone, Hemoglobin A1c, physical activity, and prostate volume. To exclude the effect of seasons, we also analyzed the impacts during each season.
Vitamin D level was lowest in winter. According to the International Prostate Symptom Score (I-PSS) and Overactive Bladder Symptom Score (OABSS), the severity of LUTS peaked in winter. There were no seasonal differences between prostate volume, peak flow rate, and post-void residual urine. For all patients, multivariate analysis showed that lower vitamin D was significantly associated with a higher total OABSS, whereas it was not associated with prostate volume, peak flow rate, post-void residual urine, and total I-PSS. In winter, lower vitamin D was significantly associated with a higher total OABSS based on multivariate analysis, whereas it was not during other seasons. In patients with vitamin D deficiency, the total OABSS significantly decreased after vitamin D replacement. The greatest improvement in total OABSS was associated with lower pre-treatment total OABSS and higher post-treatment vitamin D level.
Vitamin D decrement in men with LUTS may play a role in aggravated overactive bladder (OAB) symptoms, especially in winter. Increasing vitamin D in patients with vitamin D deficiency appears to alleviate OAB symptoms.
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