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Nanoemulsion Vitamin D faster and better (paywall) – RCT Dec 2021


Benefits of using a microencapsulated vitamin D delivery system in women with polycystic ovary syndrome

Eur J Hosp Pharm. 2021 Dec 1;ejhpharm-2021-002967. doi: 10.1136/ejhpharm-2021-002967 Paywall
Vesselina Yanachkova 1, Radiana Staynova 2, Svetoslav Stoev 3, Emilia Naseva 4

Objective: To compare and assess the efficacy of two vitamin D delivery systems (oil-based and microencapsulated) on 25-hydroxy-vitamin D (25(OH)D) levels, body mass index (BMI) and insulin resistance (IR) in women with established polycystic ovary syndrome (PCOS) and vitamin D deficiency.

Materials and methods: A monocentric, retrospective study was conducted, using the data of 70 female patients, who visited the endocrinology department of the "Dr. Shterev" Hospital, Sofia, Bulgaria between May 2020 and September 2020. The patients were divided into two groups according to the type of vitamin D3 supplementation: either a microencapsulated liposomal form (n=35), or a conventional oil-based form (n=35). The following clinical measures were analysed and compared: BMI, serum levels of 25(OH)D, fasting plasma glucose levels, fasting immunoreactive insulin (IRI), homeostatic model assessment (HOMA) index, levels of antimullerian hormone (AMH) II generation, and testosterone. In all selected patients, these measurements were performed at baseline and 3 months after initiation of vitamin D supplementation.

Results: Significantly increased serum levels of 25(OH)D were observed in patients supplemented with the microencapsulated form of vitamin D3 in the third month from the beginning of therapy, compared with the control group (p=0.003). In the microencapsulated vitamin D group, there was a decrease in IRI serum levels (p=0.023), HOMA-IR (p=0.021), serum AMH (p=0.010) and testosterone levels (p=0.006). The fasting plasma glucose levels did not change significantly.

Conclusion: The results of our study show that the patients supplemented with a microencapsulated form of vitamin D3 achieved faster compensation of 25(OH)D levels, which in turn, under equal conditions, led to significant improvement in the metabolic profile, in particular insulin sensitivity.


19+ VitaminDWiki pages with NANOEMULSION or EMULSION etc. in the title

This list is automatically updated

Items found: 20
Title Modified
Vitamin D: liposomal and nanoemulsion forms - Chat-GPT Dec 2023 30 Dec, 2023
Nanoemulsion Vitamin D is faster and better - many studies 06 Oct, 2023
Fast responses to Vitamin D – loading dose, nanoemulsion and Calcifediol – April 2023 15 Apr, 2023
Nanoemulsion Vitamin D faster and better (paywall) – RCT Dec 2021 02 Dec, 2021
COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020 21 Sep, 2021
Nanoemulsion Vitamin D may be a substantially better form 02 Jun, 2021
COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021 22 May, 2021
Inhaling Vitamin D nanoemulsion through nose gets lots more to the brain (mice) – July 2020 03 Aug, 2020
Vitamin D nanoemulsion, with comments on COVID-19 – June 2, 2020 04 Jun, 2020
Nanoemulsion vitamin D is again found to be the best liquid form (for rats in this case) – June 2019 20 Dec, 2019
Bioavailability of nanoemulsion formulations of Vitamin D3 – Nov 2019 20 Dec, 2019
Vitamin D nanoemulsion etc. for fortification, pills, injections, topical and cancer – July 2019 18 Jul, 2019
Vitamin D Emulsion update - March 2019 28 Mar, 2019
Vitamin D Emulsions - nano 2X better than coarse – Dec 2017 04 Mar, 2019
Vitamin D nanoemulsion corrected deficiency and improved bones in 1 week (high dose in rats) – Jan 2019 05 Jan, 2019
Advances in Vitamin D emulsions, nanoparticles, etc. – Jan 2019 30 Dec, 2018
Colitis treated by activated vitamin D getting into the colon via emulsion (mice) – July 2018 24 Jul, 2018
Lung cancer and inhaled emulsions (wonder about inhaled Vitamin D) – 2018 17 Jun, 2018
Inhaled nanoemulsion of Vitamin D killed lung bacteria – Sept 2017 19 Apr, 2018
Nanoemulsions of vitamin D help reduce asthma markers in mice– Dec 2013 12 Dec, 2013


See also in VitaminDWiki


Created by admin. Last Modification: Saturday September 23, 2023 22:40:37 GMT-0000 by admin. (Version 12)