Cross-sectional study of the combined associations of dietary and supplemental eicosapentaenoic acid + docosahexaenoic acid on Omega-3 Index
Nutrition Research. Available online 11 September 2019 https://doi.org/10.1016/j.nutres.2019.09.001
Sharon L.McDonnell a Christine B.French a Carole A.Baggerly a William S.Harris bc
Grassroots Health highlights of their study
- Omega-3 – Chart of index vs ratio by GrassrootsHealth – Sept 2019
- Omega-3 index - good level needed 2.4 grams of regular Omega-3 - Grassroots Nov 2018
- Omega-3 index of 6 to 7 associated with best cognition in this study – Nov 2019
- Omega-3 index - many studies
- Omega-3 index replaces the Omega-6 to Omega-3 ratio – March 2018
- No NCAA player had a healthy Omega-3 index – Jan 2019
- NCAA trainers do not appear to have gotten on board the Omega-3 train yet
- NCAA trainers are getting on board the Vitamin D train (40-50 ng)– Nov 2019
- Omega-3 index of 5 greatly decreases the risk of an early preterm birth – Dec 2018
Vitamin D and Omega-3 category starts with
415 Omega-3 items in category Omega-3 helps with: Autism (7 studies), Depression (28 studies), Cardiovascular (34 studies), Cognition (54 studies), Pregnancy (46 studies), Infant (34 studies), Obesity (14 studies), Mortality (7 studies), Breast Cancer (5 studies), Smoking, Sleep, Stroke, Longevity, Trauma (12 studies), Inflammation (19 studies), Multiple Sclerosis (9 studies), VIRUS (12 studies), etcCIlck here for details
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Studies have linked an Omega-3 Index (O3I), which measures eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA) in red blood cell membranes, of ≥8% with improved health. Previous studies found that the American Heart Association (AHA) recommendation of 1-2 seafood meals per week does not achieve an O3I ≥8% even with an EPA + DHA supplement; however, these studies did not assess the frequency or amount of supplemental intake. Among participants in a predominantly US and Canadian cohort with high nutrient supplement use, we hypothesized that those adhering to the AHA guidelines would not have an average O3I ≥8% but that those taking a daily supplement would. Fish consumption and EPA + DHA supplement use were reported by 1795 participants; 985 also completed a blood spot test for O3I. A majority (71%) consumed <2 servings per week of fatty fish, and 61% took an EPA + DHA supplement. The amount of EPA + DHA for 1 serving (based on the product label) significantly differed among the >400 supplement products (50-3570 mg). O3I was ≥8.0% in 19% of participants. Among non–supplement takers, 3% of those consuming 1 fish serving per week and 17% consuming ≥2 achieved an O3I ≥8.0%. Among those consuming ≥2 fish servings per week, only those also taking an average of 1100 mg/d of supplemental EPA + DHA had a median O3I ≥8.0%. Based on the relationship between supplemental EPA + DHA intake and O3I for non–fish eaters (R2 = 0.40, P < .0001), an average of ~1300 mg/d of EPA + DHA achieved an O3I of 8.0%. This study suggests that following the AHA guidelines does not produce an O3I ≥8% nor does taking 1 serving per day of most omega-3 supplements.