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Vitamin D paradox – Blacks need Vit D for health, but not as much D for strong bones – May 2018

The vitamin D paradox in Black Americans: a systems-based approach to investigating clinical practice, research, and public health - expert panel meeting report

BMC Proceedings, May 2018, 12:6 |
LaVerne L. Brown, Barbara Cohen, Derrick Tabor, Giovanna Zappalà, Padma Maruvadam Paul M. Coates

  • Pardox: Black Americans need less Vitamin D for strong bones than Whites
  • Apparently not mentioned in this discussion, Black American need as much vitamin D for non-bone health

See also VitaminDWiki

Overview Dark Skin and Vitamin D contains the following summary

FACT - - People with dark skins have more health problems and higher mortality rate than those with light skins
FACT - - People with dark skins have low levels of vitamin D
FACT - - People with light skins who have low vitamin D have health problems
OBSERVATION - - The health problems of whites with low level of vitamin D are similar to those with dark skins
CONCLUSION - - People with dark skins have more health problems due to low levels of vitamin D

Blacks die more often than whites of many diseases (they have less vitamin D) – 2012 contains the following summary

Cancer Facts & Figures for African Americans Cancer.org

  • “African Americans have the highest death rate and shortest survival of any racial and ethnic group in the US for most cancers”
  • Has a huge number of tables and charts, Note: Vitamin D is not mentioned

Leading Causes of Death 2012 (latest information as of March 2018)

All Ages Death rateBlackWhiteRatio
Heart diseases 217 1711.27
Cancer 199170.1.17
Cerebrovascular diseases51361.4
Diabetes 40 192.0

Rates per 100,000    Age adjusted   Non-Hispanic

Items in both categories Bone and Skin-dark are listed here:

 Download the PDF from VitaminDWiki

The Office of Dietary Supplements, the National Institute on Minority Health and Health Disparities, the National Institute on Aging, and the National Institute of Diabetes and Digestive and Kidney Diseases, all components of the U.S. National Institutes of Health, co-sponsored an expert panel meeting to discuss the vitamin D paradox in Black Americans. The paradox is that despite markedly low (or “deficient”) measures of vitamin D status in Black Americans, the incidence of falls, fractures, or osteopenia are significantly lower compared to White American counterparts with similar vitamin D status. Six panelists were invited to engage in guided discussions on the state of the science with respect to key knowledge gaps impacting vitamin D status and bone health. They were also asked to reflect on best approaches for advancing the science.

A central theme throughout the discussions was that there may be many factors that impact Vitamin D levels in Black Americans and understanding these factors may be key to understanding mechanisms for improving bone health in all populations. Data presented showed that although adiposity, skin pigmentation, vitamin D binding protein polymorphisms, and genetics all contributed to differences in 25(OH)D levels in Black vs. White Americans, no one factor alone could fully explain the vitamin D paradox in Black Americans. However, the panelists did agree that the paradox is significant and warrants further investigation.
There was consensus that Black Americans gained no skeletal benefits from high doses of vitamin D supplementation, and that high levels of the biomarker of vitamin D status, serum 25-hydroxyvitamin D or 25(OH)D, in this population are almost certain to result in adverse effects. Some panelists proposed that additional studies are needed so that the Institute of Medicine (IOM) can better define the safe upper limits of vitamin D intake in this and other subpopulations. Others suggested a need for better, more generalizable biomarkers of bone health to advance the science.

Attached files

ID Name Comment Uploaded Size Downloads
9839 vitamin D paradox in Black Americans.pdf PDF 2018 admin 12 May, 2018 12:08 707.27 Kb 6
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