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Vitamin D before and during pregnancy – Sept 2017

Vitamin D supplementation for women before and during pregnancy: an update of the guidelines, evidence, and role of GPs and practice nurses

Br J Gen Pract 2017; 67 (662): 423-424. DOI: https://doi.org/10.3399/bjgp17X692489
Catherine Hynes, Amrita Jesurasa, Patricia Evans and Caroline Mitchell

VitaminDWiki

The UK study on this page recommends just 400 IU, and is behind a $36 paywall
Yes, 400 IU during pregnancy prevents rickets.
However, far more is needed: during pregnancy: at least 2,000 IU and preferably 6,000 IU
VitaminDWiki started a FREE page in 2010 with the subtitle:
    Vitamin D Before, During, and After Pregnancy

Before - increase fertility and provide VIt D for early lung growth
During - see 17 reasons below
After - restore mon's level of vitamin D and provide Vit D in breast milk

A page summarizing of the benefits for mother and child was started in 2014

Problem
ReducesEvidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

Pregnancy category starts with

721 items in Pregnancy category

 - see also


INTRODUCTION
UK National Institute for Health and Care Excellence (NICE) guidance (2014) advises that 10 µg vitamin D should be taken by all women throughout pregnancy, ideally starting prior to conception.1,2 However, the terminology used and practicalities of implementing this advice can be confusing, as can the role of the GP and practice nurse regarding the provision of supplementation; — particularly as their involvement in routine antenatal care is tending to diminish. This article summarises the evidence and related guidance on managing vitamin D status in pregnant women, and provides an update on the ways in which women can obtain the necessary supplements.

BACKGROUND
Vitamin D is not only integral to calcium homeostasis and bone health, but it also has multiple other sites of action throughout the body, including the pancreas, skin, intestine, and immune system. In the UK, dietary sources of vitamin D are limited and account for only 10–20% of the total body store; natural sources include oily fish, egg yolk, and red meat, while fortified foods include infant and toddler formula milks, some breakfast cereals, and margarines. The majority of vitamin D is from skin synthesis following exposure to sunlight, although in the UK the necessary wavelength of ultraviolet radiation is only available between April and mid-October.1,3

Most laboratories measure serum 25-hydroxyvitamin D (25[OH]D) as a reflection of current vitamin D stores, which equates to the levels produced cutaneously and through …

Publisher wants $36 for the PDF

Created by admin. Last Modification: Friday September 1, 2017 14:01:07 GMT-0000 by admin. (Version 8)
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