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Traumatic Brain Injury recovered faster if high vitamin D (review of 58 studies) – April 2021

Optimal Vitamin D Level Ameliorates Neurological Outcome and Quality of Life after Traumatic Brain Injury: A Clinical Perspective

International Journal of Neuroscience https://doi.org/10.1080/00207454.2021.1924706
Ajay Choudhary,Ashok Kumar,Rajesh Sharma,Lipika Khurana,Smita Jain,Shallu Sharma, show all
Received 11 Jun 2020, Accepted 24 Apr 2021, Accepted author version posted online: 30 Apr 2021

VitaminDWiki

The most recently changed titles containing "Traumatic Brain Injury"

Items found: 19
Title Modified
Vitamin D3 Attenuates Blood-Brain Barrier Disruption due to TBI (in rats) – Feb 2021 23 Feb, 2021
Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT March 2020 17 Mar, 2020
Traumatic Brain Injuries treated by Vitamin D etc (US patent) – interview Dec 2019 25 Dec, 2019
Preventing and treating TBI with Vitamin D, Magnesium Omega-3, Zinc, etc – book 2011 21 May, 2019
Vitamin B12 treats Traumatic Brain Injury in mice – April 2019 21 May, 2019
Traumatic Brain Injuries routinely treated by Vitamin D, Omega-3, Progesterone and Gluatmine 15 May, 2019
Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D – March 2019 13 May, 2019
Spinal cord problems more likely if TBI if little Omega-3 in diet – June 2013 07 Oct, 2018
Dementia risk increased 2.4 X following TBI, even if had not lost consciousness – May 2018 12 May, 2018
5 Traumatic brain injuries resulted in 2.8 X increased risk of dementia – April 2018 11 Apr, 2018
Mild Traumatic Brain Injury prevented with Omega-3, Resveratrol, etc (in rats) – Oct 2017 10 Oct, 2017
Concussions (traumatic brain injury) getting big press coverage, vitamin D might be both a cause and a solution 21 Sep, 2017
Mild Traumatic Brain Injury reduced by Vitamin D – May 2014 07 Aug, 2017
Cognitive decline after traumatic brain injury reduced by Omega-3 (mice) – Nov 2016 06 Dec, 2016
Traumatic brain injury treated by Vitamin D Progesterone Omega-3 and glutamine – May 2013 11 Sep, 2016
High-fructose diet slows recovery from brain injury - TBI, rats - Oct 2015 01 May, 2016
Traumatic Brain Injury in military - vitamin D - 2014 08 Feb, 2016
Vitamin D aided progesterone in reducing traumatic brain injury – RCT Dec 2012 03 Jan, 2015
Traumatic Brain Injury recovered faster if high vitamin D (review of 58 studies) – April 2021 No value for 'modification_date_major'


Background Deficiency of vitamin D along with traumatic brain injury (TBI) augments the risk of injury severity. This possibly affects the therapeutic regimen prescribed for TBI which may pessimistically affects its outcome.

Methods Studies literature search was conducted in Google Scholar and PubMed. The inclusions were studies performed clinically on both male and female. All included studies’ references were also reviewed to find any additional relevance related to this review. Studies published in English were considered for this review. This review focuses upon the incidence of vitamin D deficiency in TBI and how it affects the Quality of life of the sufferer.

Results A total of 176 studies were reviewed and 58 were thoroughly focussed for review as they met inclusion criteria. These studies demonstrate that levels of vitamin D influence the recovery outcome after TBI. Vitamin D deficiency has been found to cause more deterioration in severe TBI than in patients with mild TBI.

Conclusion Paucity of vitamin D significantly affects the outcome after brain injury. This clearly validates the necessity for screening of vitamin D levels in neurological deficit in order to reduce the risk of morbidity in terms of neurocognitive disorder.


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