Optimal Vitamin D Level Ameliorates Neurological Outcome and Quality of Life after Traumatic Brain Injury: A Clinical Perspective
International Journal of Neuroscience https://doi.org/10.1080/00207454.2021.1924706
Ajay Choudhary,Ashok Kumar,Rajesh Sharma,Lipika Khurana,Smita Jain,Shallu Sharma, show all
Background Deficiency of vitamin D along with traumatic brain injury (TBI) augments the risk of injury severity. This possibly affects the therapeutic regimen prescribed for TBI which may pessimistically affects its outcome.
Methods Studies literature search was conducted in Google Scholar and PubMed. The inclusions were studies performed clinically on both male and female. All included studies’ references were also reviewed to find any additional relevance related to this review. Studies published in English were considered for this review. This review focuses upon the incidence of vitamin D deficiency in TBI and how it affects the Quality of life of the sufferer.
Results A total of 176 studies were reviewed and 58 were thoroughly focussed for review as they met inclusion criteria. These studies demonstrate that levels of vitamin D influence the recovery outcome after TBI. Vitamin D deficiency has been found to cause more deterioration in severe TBI than in patients with mild TBI.
Conclusion Paucity of vitamin D significantly affects the outcome after brain injury. This clearly validates the necessity for screening of vitamin D levels in neurological deficit in order to reduce the risk of morbidity in terms of neurocognitive disorder.
VitaminDWiki items with "Traumatic Brain Injury" or "TBI" in the title (19 as of June 2022)
Items found: 21
Title |
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Modified |
How Vitamin D treats Traumatic Brain Injury – July 2022 |
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26 Jan, 2023 |
40% less likely to recover from TBI with Intracranial Injury if low vitamin D – June 2022 |
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09 Jun, 2022 |
Traumatic Brain Injury recovered faster if high vitamin D (review of 58 studies) – April 2021 |
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09 Jun, 2022 |
Vitamin D3 Attenuates Blood-Brain Barrier Disruption due to TBI (in rats) – Feb 2021 |
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23 Feb, 2021 |
Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT March 2020 |
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17 Mar, 2020 |
Traumatic Brain Injuries treated by Vitamin D etc (US patent) – interview Dec 2019 |
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25 Dec, 2019 |
Preventing and treating TBI with Vitamin D, Magnesium Omega-3, Zinc, etc – book 2011 |
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21 May, 2019 |
Vitamin B12 treats Traumatic Brain Injury in mice – April 2019 |
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21 May, 2019 |
Traumatic Brain Injuries routinely treated by Vitamin D, Omega-3, Progesterone and Gluatmine |
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15 May, 2019 |
Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D – March 2019 |
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13 May, 2019 |
Spinal cord problems more likely if TBI if little Omega-3 in diet – June 2013 |
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07 Oct, 2018 |
Dementia risk increased 2.4 X following TBI, even if had not lost consciousness – May 2018 |
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12 May, 2018 |
5 Traumatic brain injuries resulted in 2.8 X increased risk of dementia – April 2018 |
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11 Apr, 2018 |
Mild Traumatic Brain Injury prevented with Omega-3, Resveratrol, etc (in rats) – Oct 2017 |
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10 Oct, 2017 |
Concussions (traumatic brain injury) getting big press coverage, vitamin D might be both a cause and a solution |
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21 Sep, 2017 |
Mild Traumatic Brain Injury reduced by Vitamin D – May 2014 |
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07 Aug, 2017 |
Cognitive decline after traumatic brain injury reduced by Omega-3 (mice) – Nov 2016 |
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06 Dec, 2016 |
Traumatic brain injury treated by Vitamin D Progesterone Omega-3 and glutamine – May 2013 |
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11 Sep, 2016 |
High-fructose diet slows recovery from brain injury - TBI, rats - Oct 2015 |
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01 May, 2016 |
Traumatic Brain Injury in military - vitamin D - 2014 |
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08 Feb, 2016 |
Vitamin D aided progesterone in reducing traumatic brain injury – RCT Dec 2012 |
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03 Jan, 2015 |