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Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D – March 2019

The Effect of Vitamin D Supplementation in Patients with Acute Traumatic Brain Injury

World Neurosurgery, online 20 March 2019, https://doi.org/10.1016/j.wneu.2019.02.244

VitaminDWiki

This study used just a small injection of Vitamin D
100,000 IU of Vitamin D will raise the blood level a little bit
Loading doses of 400,000 and 600,000 IU of Vitamin D have been used >1 million times
   By the way - I take 100,000 IU of vitamin D every 4 days (founder of VitaminDWiki May 2019)


TBI appears to be prevented and/or treated by getting more vitamin D in the brain

Each of the following help, some combination should be really good

  1. Progesterone (VDR)
  2. Omega-3 (VDR)
  3. Resveratrol (VDR)
  4. Magnesium (VDR and blood)
  5. Vitamin D

Wonder which additonal VDR activators might also prevent/treat TBI

Vitamin D Receptor table shows what compensates for low VDR activation

Compensate for poor VDR by increasing one or more:

IncreasingIncreases
1) Vitamin D supplement
  Sun, Ultraviolet -B
Vitamin D in the blood
and thus to the cells
2) MagnesiumVitamin D in the blood
 AND to the cells
3) Omega-3 Vitamin D to the cells
4) Resveratrol Vitamin D to the cells
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
etc
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation.
You might feel the benefit within days of adding one or more of the above

51 diseases were strongly associated with Vitamin D Receptor as of April 2019


Trauma and surgery category starts with the following

Trauma and Surgery category has 240 articles

see also Concussions
Overview Fractures and Falls and Vitamin D
Cancer - After diagnosis   chemotherapy
Search VitaminDWiki for TBI OR "Traumatic Brain Injury" 690 items as of May 2019
Search VitaminDWiki for cathelecidin OR hCAP18 187 items as of May 2019
Search VitaminDWiki for ICU OR “critical care” OR “intensive care” OR “acute care”
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Search VitaminDWiki for transplant 794 items as of Jan 2018

 Download the PDF Sci-Hub via VitaminDWiki

Objective: To investigate the acute and long-term effects of vitamin D supplementation on the recovery of patients with traumatic brain injury (TBI).

Methods
A retrospective study was conducted involving 345 patients with TBI who visited a single trauma center. Vitamin D serum levels were measured without supplementation at admission, 1 month, and 3 months post-TBI (control group) from August to December 2016. From January 2017, vitamin D supplementation was provided to patients with TBI with low vitamin D serum levels at admission (supplement group). The outcomes were investigated by assessing performance function (Extended Glasgow Outcome Scale) and cognitive function (Mini-Mental Status Examination, and Clinical Dementia Rating) at 1 week and 3 months post-TBI.

Results
The mean vitamin D serum level in patients with TBI at admission was 13.62 ± 9.01 ng/mL. The level significantly increased from 14.03 ± 8.68 ng/mL at admission to 37.42 ± 12.57 ng/mL at 3 months post TBI in the supplement group (P < 0.001). The cognitive outcomes (Mini-Mental Status Examination/Clinical Dementia Rating, P = 0.042/P = 0.044) and GOS-E score (total TBI, P = 0.003; mild-to-moderate TBI, P = 0.002) significantly improved from the first week to 3 months post TBI in the patients with vitamin D supplementation.

Conclusions
Administration of vitamin D supplements in mild-to-moderate TBI patients with significant vitamin D deficiency during the acute phase of the injury may improve long-term performance and cognitive outcomes. Therefore, the treatment strategies should be individually planned for the patients with TBI based on their baseline vitamin D level.

Created by admin. Last Modification: Tuesday May 14, 2019 20:59:27 GMT-0000 by admin. (Version 7)

Attached files

ID Name Comment Uploaded Size Downloads
11947 TBI.pdf PDF 2019 admin 13 May, 2019 18:24 196.01 Kb 3
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