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Periodontitis problems often 3X more likely if poor Vitamin D receptor – May 2022

Profile of vitamin D receptor gene polymorphism TaqI in patients with periodontitis

Biomed Rep. 2022 May;16(5):35. doi: 10.3892/br.2022.1518
Nurlindah Hamrun 1, Muhammad Ruslin 2, Erni Marlina 3, Sri Oktawati 4, Takashi Saito 5, Andi Sitti Hajrah Yusuf 2, Keng-Liang Ou 6 7


The present study aimed to assess the incidence of the vitamin D receptor (VDR) gene polymorphism TaqI in patients with periodontitis, and the potential association of this polymorphism with the severity of the disease. This was a case-controlled study, which included 162 adults divided into two groups as follows: Case group (81 patients diagnosed with periodontitis) and control group (81 patients without periodontitis). Venous blood was obtained from each sample from which DNA was extracted. The gene polymorphism was determined using restricted fragment length polymorphism-PCR and DNA sequencing to identify endonuclease restrictions in exon 9 (TaqI). The data were analyzed using an independent samples t-test. VDR gene polymorphisms were detected in periodontitis cases with TT (86.4%), Tt (12.4%) and tt (1.2%) genotypes. DNA sequencing confirmed a change in the sequence of the VDR gene nucleotides in patients with periodontitis. The data indicated that the severity of periodontal tissue damage may be influenced by changes in the nucleotide sequence.
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VitaminDWiki - The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (19 studies), Breast Cancer (22 studies), Colon Cancer (13 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (24 studies), Hypertension (9 studies), Infant (21 studies), Lupus (6 studies), Metabolic Syndrome (4 studies), Mortality (4 studies), Multiple Sclerosis (12 studies), Obesity (16 studies), Pregnancy (24 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (35 studies),   Click here for details
Some health problems, such as Breast Cancer and Diabetes, protect themselves by reducing VDR activation
Suspect that SAR-COV-2 also protects itself from Vitamin D

VitaminDWiki - Ways to increase VDR activation

Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise,   Ginger,   Essential oils, etc Note: The founder of VitaminDWiki uses 10 of the 13 known VDR activators

Created by admin. Last Modification: Thursday April 7, 2022 18:40:00 GMT-0000 by admin. (Version 10)

Attached files

ID Name Comment Uploaded Size Downloads
17351 VDR perodontitis.jpg admin 07 Apr, 2022 45.87 Kb 221
17350 VDRR periodontitis.pdf admin 07 Apr, 2022 801.55 Kb 218