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Omega-3 proven to provide many benefits in 5 year VITAL trial - Nov 2018

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Same information as above,
but includes probability information and can be translated to other languages


Statistically Significant Omega-3 Results from
Pre-specified Secondary Outcomes and Subgroup Analyses
p <0.05 for the association to be probable
Smaler p = more probable

Omega-3 vs. Placebo Secondary OutcomesReduced
Risk
p
Heart Attack28% p=0.002)
Major CVD event (heart attack, stroke,
or death from cardiovascular cause)
Fish consumption <1.5 servings/wk19% p=0.03)
African Americans with <1.5 servings of fish/wk39% p=0.049)
Secondary Outcomes - Subgroup Analyses
Heart Attack
African Americans77% p=<0.0001)
African Americans with diabetes94% p=0.005)
African Americans with 1 cardiovascular risk factor72% p=0.047)
African Americans with 2+ cardiovascular risk factors84% p=0.001)
Fish consumption <1.5 servings/wk40% p=0.0007)
Non-Hispanic Caucasians with <1.5 servings of fish/wk29% p=0.04)
African Americans with <1.5 servings of fish/wk77% p=0.003)
African Americans with ≥1.5 servings of fish/wk79% p=0.01)
Age <66.7 years (median age)40% p=0.005)
Males28% p=0.02)
Non-current Smokers21% p=0.04)
Current Smokers62% p=0.02)
Medication-treated diabetes60% p=0.0003)
Medication-treated hypertension42% p=0.0002)
Taking cholesterol medication35% p=0.02)
Without parental history of heart attack29% p=0.008)
Not assigned to vitamin D29% p=0.02)
With 2+ cardiovascular risk factors43% p=0.001)
With baseline aspirin use36% p=0.007)
With baseline statin use32% p=0.04)
All-Cause Mortality
African Americans with <1.5 servings of fish/wk36% p=0.03)
Omega-3 vs. Placebo Post-Hoc Outcomes
Death from Heart Attack50% p=0.04)
Percutaneous coronary intervention (PCI; stent) 22% p=0.02)
Coronary heart disease (heart attack, PCI, CVD death)17% p=0.02)

See also VitaminDWiki

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Vitamin D and Omega-3 category starts with

394 Omega-3 items in category Omega-3 helps with: Autism (8 studies), Depression (29 studies), Cardiovascular (34 studies), Cognition (49 studies), Pregnancy (40 studies), Infant (32 studies), Obesity (13 studies), Mortality (7 studies), Breast Cancer (5 studies), Smoking, Sleep, Stroke, Longevity, Trauma (12 studies), Inflammation (18 studies), Multiple Sclerosis (9 studies), VIRUS (12 studies), etc
CIlck here for details

Omega-3 and Meta-analysis (items in both categories)


Review of the study by the Washington Post - April 2019

Don’t throw away your vitamin D supplements yet
"The VITAL study was poorly designed and the results have not been adequately explained in the abstract and in the press coverage. The vitamin D status of many participants was above average and the dose (2000 IU/d vitamin D3) was too low to find beneficial results for cancer incidence for the entire group. However, for those with BMI <25 kg/m2, there was a 24% reduction in all-cancer incidence. For blacks, who have lower vitamin D status than whites, there was a 23% reduction in all-cancer incidence. When the first 1-2 years of the study are omitted, there was a 21 and 25% reduction in all-cancer mortality rate. Thus, this study adds to the literature that UVB exposure and vitamin D reduce the risk of cancer incidence and mortality. Had the authors designed and analyzed the results based on achieved vitamin D status, the results would have been much stronger. One wonders whether the reporting of the results has buried the positive findings in order to benefit our disease-treatment system rather than to reduce the burden of unnecessary disease."


Created by admin. Last Modification: Sunday November 7, 2021 22:41:23 GMT-0000 by admin. (Version 15)

Attached files

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10938 VITAL table.jpg admin 30 Nov, 2018 149.74 Kb 457