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Vitamin D associated with better self-rated health in male employees – June 2016

Vitamin D Status and Quality of Life in Healthy Male High-Tech Employees

Nutrients 2016, 8(6), 366; doi:10.3390/nu8060366 Published: 15 June 2016
Sigal Tepper h sigalt at bgu.ac.il, Yael Dabush , Danit R. Shahar , Ronit Endevelt, Diklah Geva 1 and Sofia Ish-Shalom
The S. Daniel Abraham International Center for Health and Disease, Department of Public Health, Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva 8410501, Israel; dshahar at bgu.ac.il (D.R.S.); diklah.geva at gmail.com (D.G.)
Department of Clinical Nutrition, Rambam Health Care Campus, Haifa 31093, Israel; yaelidabush at gmail.com
School of Public Health, Haifa University, Mt. Carmel, Haifa 31905, Israel; ronit.endevelt at moh.gov.il
Department of Endocrinology & Diabetes, Elisha Medical Center, Haifa 3463626, Israel; sishshalom at gmail.com


Table 2 (nanograms/mL)

<12 12–20 >20
Self-rated health excellent,
very good, good
87% 89% 96%
Self-rated health fair, poor 13% 11% 4%
  • Note: I have had Vitamin D levels of ~100 ng/mL for 5 years - with EXCELLENT healthy (age 70)    Henry Lahore, founder of VitaminDWiki

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While low vitamin D status has been shown to be associated with decreased quality
of life in unhealthy populations and women, only limited data are available regarding healthy
adult men. Our aim was to evaluate the associations between health-related quality of life (QoL)
and vitamin D status in adult men. High-tech employees aged 25–65 year were recruited from
an occupational periodic examination clinic at Rambam Health Campus. QoL was assessed using
the Centers for Disease Control and Prevention (CDC) Health-related quality of life questionnaire
(HRQOL-4). Serum 25-hydroxyvitamin D (25(OH)D) and Body Mass Index (BMI) were measured;
further information was collected about physical activity, education, sun exposure, sick-days, and
musculoskeletal pain severity (visual analog scale). Three hundred and fifty-eight men were
enrolled in the study; mean serum 25(OH)D level was 22.1 ˘ 7.9 ng/mL (range 4.6–54.5 ng/mL).
In a multivariate logistic regression model, 25(OH)D was a significant independent determinant
of self-rated health; Odds Ratio (OR) for self-rated health was 0.91 (95% confidence interval (CI)
0.85–0.97, p = 0.004), adjusted for age, BMI, pain severity, physical activity, and sun exposure.
Every 1 ng/mL increase of 25(OH)D was associated with 9% reduction in the odds of reporting
self-rated health as fair or poor. Poisson regression model demonstrated an association between
physically unhealthy days and 25(OH)D levels (rate ratio 0.95, p < 0.001). In conclusion, serum levels
of 25(OH)D were associated with self-rated health and with physically unhealthy days of HRQOL
in healthy high-tech male workers. Future intervention studies are required to test the impact of
vitamin D supplementation on QoL.

Attached files

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6791 QoL.pdf PDF 2016 admin 15 Jun, 2016 16:32 223.85 Kb 561
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