Association of circulating 25-hydroxyvitamin D with mental well-being in a population-based, nationally representative sample of German adolescents.
Qual Life Res. 2016 Jun 24. [Epub ahead of print]
Schäfer TK1, Herrmann-Lingen C1, Meyer T2.
1Department of Psychosomatic Medicine and Psychotherapy, German Centre for Cardiovascular Research, University of Göttingen Medical Centre, University of Göttingen, Waldweg 33, 37073, Göttingen, Germany.
2Department of Psychosomatic Medicine and Psychotherapy, German Centre for Cardiovascular Research, University of Göttingen Medical Centre, University of Göttingen, Waldweg 33, 37073, Göttingen, Germany. thomas.meyer at med.uni-goettingen.de.
Scores of previous studies have associated a higher quality of life with higher levels of vitamin D.
So, no surpise to find that higher level of vitamin D help German teens as well
__Some studies have found an increased quality of life after supplementation
- Vitamin D supplementation improved quality of life – Aug 2015
- 400,000 IU of vitamin D reduced adult pain and improved quality of life – March 2014
- Quality of life increased with increased levels of vitamin D – April 2014
- Vitamin D associated with better self-rated health in male employees – June 2016
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Numerous studies have linked vitamin D to health-related quality of life (hrQoL) in chronically ill adults or elderly subjects. The aim of this study was to evaluate the association between 25-hydroxyvitamin D (25(OH)D) and hrQoL in a population-based sample of German adolescents.
A total of n = 5066 study participants from the nationwide, representative German Health Interview and Examination Survey for Children and Adolescents (Kinder- und Jugendgesundheitssurvey) aged 11-17 years were included in this post hoc analysis. HrQoL was measured using the well-validated self- and parent-rated Children's Quality of Life questionnaires (KINDL-R), while the level of distress was assessed using the self- and proxy version of the Strengths and Difficulties Questionnaire (SDQ). Serum 25(OH)D concentrations were determined using a commercially available chemiluminescence immunoassay.
Bivariate analyses demonstrated a significant positive association between 25(OH)D and hrQoL for both self- [estimate (E) = 0.82, 95 % confidence interval (95 % CI) 0.35-1.30, p = 0.001] and parent ratings (E = 1.33, 95 % CI 0.83-1.83, p < 0.001). In addition, we found negative correlations between 25(OH)D and self- (E = -0.34, 95 % CI -0.58 to -0.11, p = 0.005) and parent-reported total SDQ scores (E = -0.70, 95 % CI -1.03 to -0.37, p < 0.001). Generalized linear models adjusted for age, sex, body mass index, systolic blood pressure, migration background, socio-economic status, and sedentary screen time confirmed that 25(OH)D independently and significantly predicted better hrQoL (p = 0.004).
These findings linking 25(OH)D to better well-being in a nationally representative sample of German children and adolescents suggest beneficial effects of vitamin D on mental health. However, recommendations for vitamin supplementation in healthy children and adolescents are not warranted from our data.
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