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Vitamin D needed for 12 ng in winter in Finland – Whites 320 IU, Blacks 720 IU – July 2018

Differences in the dietary requirement for vitamin D among Caucasian and East African women at Northern latitude

European Journal of Nutrition, pp 1–11 | https://doi.org/10.1007/s00394-018-1775-1
Kevin D. Cashman, Christian Ritz, Folasade A. Adebayo, Kirsten G. Dowling, Suvi T. Itkonen, Taina Öhman, Essi Skaffari, Elisa M. SaarnioMairead KielyChristel Lamberg Allardt

VitaminDWiki

Note: Virtually none achieved 30 ng, even with up to 2,000 IU of daily intake
Note: Only 2 or 3 countries on Earth consider 12 ng to be acceptable
Most countries have found major health problems with a 12 ng level
Most countries have a target of 30 ng, not 12 ng
Lots of research suggests that the goal should be 40, 50, or even higher levels of vitamin D


See also VitaminDWiki

Healthy pregnancies need lots of vitamin D has the following summary

Problem
ReducesEvidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

PDF is available free at Sci-Hub  10.1007/s00394-018-1775-1
Image
Note: Virtually no women got above 30 ng with up to 2,000 IU of daily vitamin D

Context
Current vitamin D recommendations have been established based on an assumption that there are no differences between Caucasian and other ethnic/racial groups in terms of vitamin D requirements. This assumption, largely made due to the absence of data, is a key knowledge gap identified by a number of authorities.

Objective
To test whether the distribution of dietary requirements for maintaining winter serum 25-hydroxyvitamin D [25(OH)D] concentrations ≥ 30 nmol/L (a priority threshold linked to vitamin D deficiency prevention) differ between Caucasian and Somali women living at northerly latitude.

Methods
We used data from a 5-month, winter-based, vitamin D3 dose-related randomized, placebo-controlled trial in Somali (n 47) and Causcian women (n 69), aged 21–64-year old, living in Southern Finland (60°N), to model the vitamin D intake–serum 25(OH)D dose–response relationship. Regression analyses were used to predict the vitamin D intake required to maintain 97.5% (as well as 50, 90, and 95%) of women in both ethnic groups above serum 25(OH)D thresholds of 30, 40 and 50 nmol/L.

Results
Using a model which adjusted for baseline 25(OH)D, age, and BMI, the estimated vitamin D intake that maintained serum 25(OH)D ≥ 30 nmol/L in 97.5% of Caucasian and Somali women was 8 and 18 µg/day, respectively. Ethnic differences were also evident at 40 and 50 nmol/L serum 25(OH)D thresholds.

Conclusion
The present study adds further evidence that ethnic differences in the dietary requirement for vitamin D do exist and that dose–response vitamin D intervention studies are required in at-risk target populations specified by ethnicity.

Created by admin. Last Modification: Monday May 13, 2019 10:20:21 GMT-0000 by admin. (Version 6)

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