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Eyes with poor blood drainage (RVO) have very low levels of vitamin D – March 2017

Serum vitamin D levels in Indian patients with retinal venous occlusions

Saudi Journal of Ophthalmology. online 28 March 2017, http://doi.org/10.1016/j.sjopt.2017.03.005
Avadhesh Oli, , D. Joshi
   BVO          CRVO          Normal


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To estimate serum vitamin D (25 OH D) level in patients of retinal vein occlusion (RVO) and compare it with age-matched controls.

Methods and material
Forty patients above 18 years of age with retinal vein occlusion and forty age-matched controls underwent serum vitamin D (Vit D) level estimation using a standard protocol. Student’s t test was used to analyse differences between the mean of two groups.

The mean age in RVO and control group was 60.25 and 60.73 years respectively. The mean (±SD) level of vitamin D in RVO patients was 13.68 (±4.58) ng/mL (range 5.5–24.8), and the 95% CI of mean was 12.21–15.14 with SD 4.58 while in control group it was 23.03 (±2.89) ng/ml (range 18.4–30.1) with 95% CI of mean being 22.11–23.96 with SD 2.89 (p value of <0.005). While comparing the level of Vitamin D based on type of occlusion the mean level of Vit D in CRVO patients was 15.36 (SD 5.30) and in BRVO it was 12.77 (SD 3.96) which was statistically not significant (p = 0.08). The odds ratio calculated for RVO cases versus controls was 133.33 which was statistically significant (P < 0.05).

There is a paucity of published literature on level of Vit D in RVO. This study shows significantly lower levels of serum vitamin D in Indian patients with retinal vein occlusion as compared to age matched controls. Establishment of this correlation has possible implications for prophylaxis or treatment of RVOs.

Attached files

ID Name Comment Uploaded Size Downloads
7904 RVO.jpg admin 09 Apr, 2017 8.18 Kb 1244
7903 retinal venous occulsions.pdf admin 09 Apr, 2017 482.48 Kb 852