Int. J. Mol. Sci. 2022, 23(8), 4226; https://doi.org/10.3390/ijms23084226
by Hei-Nga Chan 1,†,Xiu-Juan Zhang 1,†,Xiang-Tian Ling 1,Christine Huyen-Trang Bui 1,Yu-Meng Wang 1,Patrick Ip 2ORCID,Wai-Kit Chu 1,3ORCID,Li-Jia Chen 1,3,4ORCID,Clement C. Tham 1,3,4,5,6ORCID,Jason C. Yam 1,3,4,5,6,*ORCID and Chi-Pui Pang 1,3,*
PDF Table of contents
The contributory roles of vitamin D in ocular and visual health have long been discussed, with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper, we provide a systematic review of recent findings on the association between vitamin D and different ocular diseases, including myopia, age-related macular degeneration (AMD), glaucoma, diabetic retinopathy (DR), dry eye syndrome (DES), thyroid eye disease (TED), uveitis, retinoblastoma (RB), cataract, and others, from epidemiological, clinical and basic studies, and briefly discuss vitamin D metabolism in the eye. We searched two research databases for articles examining the association between vitamin D deficiency and different ocular diseases. One hundred and sixty-two studies were found.
There is evidence on the association between vitamin D and myopia, AMD, DR, and DES. Overall,
- 17 out of 27 studies reported an association between vitamin D and AMD, while
- 48 out of 54 studies reported that vitamin D was associated with DR, and
- 25 out of 27 studies reported an association between vitamin D and DES.
However, the available evidence for the association with other ocular diseases, such as glaucoma, TED, and RB, remains limited.
Download the PDF from VitaminDWiki
VitaminDWiki – Vision category contains
- Myopia, AMD, Dry Eye, and Diabetic Retinopathy are all associated with low Vitamin D - April 2023
- An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022
- Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019
- Vitamin D treats and prevents a variety of eye problems (need 70 ng) – June 2018
- Vitamin D and Myopia, AMD, Diabetic Retinopathy, Uveitis, Glaucoma, VDR etc. – May 2015
- Tears often have 25 % higher levels of vitamin D than does blood
Many studies on a vision problem
- Age-Related Macular Degeneration and Vitamin D - many studies
- Cataracts and Vitamin D - many studies
- Diabetic Retinopathy associated with low Vitamin D - many studies
- 7+ studies of Glaucoma and Vitamin D
- 21+ studies of Myopia and Vitamin D
|363 visitors, last modified 24 Apr, 2023,