Saudi Journal of Ophthalmology. online 28 March 2017, http://doi.org/10.1016/j.sjopt.2017.03.005
Avadhesh Oli, , D. Joshi
BVO CRVO Normal
Vision category starts with the following
- Myopia, AMD, Dry Eye, and Diabetic Retinopathy are all associated with low Vitamin D - April 2023
- An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022
- Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019
- Vitamin D treats and prevents a variety of eye problems (need 70 ng) – June 2018
- Vitamin D and Myopia, AMD, Diabetic Retinopathy, Uveitis, Glaucoma, VDR etc. – May 2015
- Tears often have 25 % higher levels of vitamin D than does blood
Many studies on a vision problem
- Age-Related Macular Degeneration and Vitamin D - many studies
- Cataracts and Vitamin D - many studies
- Diabetic Retinopathy associated with low Vitamin D - many studies
- 7+ studies of Glaucoma and Vitamin D
- 21+ studies of Myopia and Vitamin D
- Stroke is 13.5 X more likely if low vitamin D and high blood pressure – March 2015
Suspect that RVO may also be more likely with high blood pressure
- Vitamin K2-7 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Hypothesis: Vitamin K will reduce prostate blood vessel problems – Jan 2015
Suspect that Vitamin K2 would also reduce RVO
- Central Retinal Vein Occlusion Associated With Severe Vitamin D Deficiency April 2016
- The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia 2010, about 4 in 1,000 people - Full free PDF online
- Central Retinal Vein Occlusion Clinical Presentation Medscape June 2016
- Central retinal vein occlusion Wikipedia
To estimate serum vitamin D (25 OH D) level in patients of retinal vein occlusion (RVO) and compare it with age-matched controls.
Methods and material
Forty patients above 18 years of age with retinal vein occlusion and forty age-matched controls underwent serum vitamin D (Vit D) level estimation using a standard protocol. Student’s t test was used to analyse differences between the mean of two groups.
The mean age in RVO and control group was 60.25 and 60.73 years respectively. The mean (±SD) level of vitamin D in RVO patients was 13.68 (±4.58) ng/mL (range 5.5–24.8), and the 95% CI of mean was 12.21–15.14 with SD 4.58 while in control group it was 23.03 (±2.89) ng/ml (range 18.4–30.1) with 95% CI of mean being 22.11–23.96 with SD 2.89 (p value of <0.005). While comparing the level of Vitamin D based on type of occlusion the mean level of Vit D in CRVO patients was 15.36 (SD 5.30) and in BRVO it was 12.77 (SD 3.96) which was statistically not significant (p = 0.08). The odds ratio calculated for RVO cases versus controls was 133.33 which was statistically significant (P < 0.05).
There is a paucity of published literature on level of Vit D in RVO. This study shows significantly lower levels of serum vitamin D in Indian patients with retinal vein occlusion as compared to age matched controls. Establishment of this correlation has possible implications for prophylaxis or treatment of RVOs.