Vitamin D and Heart Failure
Current Heart Failure Reports, pp 1–11, Aug 2017, https://doi.org/10.1007/s11897-017-0355-7
D. Marshall Brinkley, Omair M. Ali, Sandip K. Zalawadiya ,Thomas J. Wang
- Chronic Heart Failure not treated by Vitamin D, if dose size is ignored – meta-analysis Oct 2015 Wonder if the study on this page alos failed to consider dose size
- Chronic Heart Failure improved with 4,000 IU daily for a year – RCT April 2016
- Cardiovascular deaths 12 percent less likely if have 10 ng more vitamin D – meta-analysis March 2017
- Coronary Artery Disease without diabetes 5 times more likely if VDR gene problems – meta-analysis May 2016
- Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015
- More than 800 mg of Calcium increases Cardiovascular events by 85 percent– Nov 2011 Wonder if the study on this page looked at interaction with Calcium
- Congestive heart failure in infants virtually cured by 1000 IU of vitamin D – RCT Feb 2012
Cardiovascular category starts with the following
- Overview Cardiovascular and vitamin D
- Hypertension and vitamin D
- Overview Metabolic Syndrome and vitamin D
- Overview Stroke and vitamin D
- Heart Attack 647 items as of May 2018
- Arrhythmia OR “atrial fibrillation” 497 items as of May 2018
- (Arrhythmia OR “atrial fibrillation”) AND Magnesium 345 items as of May 2018
- "C-Reactive Protein" 1530 items as of June 2019
- TRIGLYCERIDES 863 items as of May 2018
- "Peripheral Artery Disease" 170 items as of July 2019
- "Sudden Cardiac Arrest" 98 items as of May 2018
- Search VitaminDWiki for CHF or "HEART FAILURE" 1220 items as of Aug 2017
- Search VitaminDWiki for Atherosclerosis 1510 items as of July 2019
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Overview Cholesterol and vitamin D
- Statins and vitamin D statins often reduce levels of vitamin D
Purpose
Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascular disease have low vitamin D status, making it a potential therapeutic target. We review the rationale and potential role of vitamin D supplementation in the prevention and treatment of chronic heart failure.
Recent Findings.
Substantial observational evidence has associated low vitamin D status with the risk of heart failure, ventricular remodeling, and clinical outcomes in heart failure, including mortality. However, trials assessing the influence of vitamin D supplementation on surrogate markers and clinical outcomes in heart failure have generally been small and inconclusive.
Summary
There are insufficient data to recommend routine assessment or supplementation of vitamin D for the prevention or treatment of chronic heart failure. Prospective trials powered for clinical outcomes are warranted.
Publisher wants $40 for the PDF
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