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Chronic Heart Failure – not enough evidence that Vitamin D helps (but lots of evidence for other cardiovascular problems) – Aug 2017

Vitamin D and Heart Failure

Current Heart Failure Reports, pp 1–11, Aug 2017, https://doi.org/10.1007/s11897-017-0355-7
D. Marshall Brinkley, Omair M. Ali, Sandip K. Zalawadiya ,Thomas J. Wang

See also VitaminDWiki

Cardiovascular category starts with the following

457 items In Cardiovascular category

Cardio Meta-analyses: 32 studies


Cholesterol, Statins

Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascular disease have low vitamin D status, making it a potential therapeutic target. We review the rationale and potential role of vitamin D supplementation in the prevention and treatment of chronic heart failure.

Recent Findings.
Substantial observational evidence has associated low vitamin D status with the risk of heart failure, ventricular remodeling, and clinical outcomes in heart failure, including mortality. However, trials assessing the influence of vitamin D supplementation on surrogate markers and clinical outcomes in heart failure have generally been small and inconclusive.

There are insufficient data to recommend routine assessment or supplementation of vitamin D for the prevention or treatment of chronic heart failure. Prospective trials powered for clinical outcomes are warranted.

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