Loading...
 
Toggle Health Problems and D

Cancer in children (Leukemia) more likely to recur if 20-30 ng of vitamin D – Nov 2022


Vitamin D abnormalities of children with recurrence of malignancy and comparison with newly diagnosed patients

Caspian J Intern Med . 2022 Fall;13(4):735-740. doi: 10.22088/cjim.13.4.735.
Nahid Reisi 1 , Azar Mirzaei 2 , Alireza Moafi 1 , Pouran Raeissi 3 , Maryam Naghdhassani 4

A = Leukemia recur, B = new Leukemia, C = Healthy
Image
Background: Vitamin D (Vit-D) is a necessary ingredient for human growth and its deficiency may increase the risk of cancer and its recurrence. The main purpose of this research was to assess the levels of Vit-D in children with recurrence of malignancy and compare it with new cases of malignancy and the control group.

Methods: The status of 25(OH) Vit-D was determined utilizing the HPLC method in 47 patients with recurrence of malignancy (group A), 50 children with new malignancy (group B ) and 49 normal healthy siblings of the two groups as a control (group C).

Results: Vit-D was low (<30 ng/ml) in the 92% of patients with recurrence of malignancy, which was a significant difference compared to groups B (60%) and C (45%). Vit-D insufficiency (10-30 ng/dl) in group A was also higher than the other two groups. The mean levels of Vit-D in patients with recurrence were significantly lower than the new cases and controls. Low Vit-D (<30 ng/ml) in group A in both male and female, and also in all ages (<6 and ≥ 6 years) was higher than groups B and C. Also, low Vit-D in terms of the type of malignancy in group A was higher than group B only in leukemic patients while this was not different for non-leukemic patients in these two groups.

Conclusion: Results of this study showed an increased prevalence of low Vit-D in children with recurrence of malignancies. Therefore, it may increase the risk of recurrence of malignancies in children.

 Download the PDF from VitaminDWiki


VitaminDWiki Infant-Child pages with CANCER in the title

This list is automatically updated

Items found: 16
Title Modified
Childhood Cancers - Vitamin D can help - many studies 20 Jan, 2024
Childhood Cancer Survivors have worse arteries due to anticancer therapy – May 2023 30 May, 2023
Cancer in children (Leukemia) more likely to recur if 20-30 ng of vitamin D – Nov 2022 25 Nov, 2022
Cancer during childhood - many studies 25 Nov, 2022
Poor prognosis of solid childhood cancers 14.7 X more likely with a poor Vitamin D Receptor – July 2022 27 Jul, 2022
Newly diagnosed Children with Cancer have low vitamin D, especially if black - May 2022 16 Jun, 2022
Cancer of the eye in children: most of the risk factors are associated with low vitamin D – July 2021 26 Dec, 2021
Childhood cancers – give Vitamin D loading dose if low – Oct 2021 27 Oct, 2021
Children's Cancer hospital now testing vitamin D frequently and supplementing weekly – July 2021 22 Jul, 2021
Consensus recommends at least 20 ng of Vitamin D for childhood cancer (not nearly enough) – June 2021 08 Jun, 2021
Relapses of Acute Lymphoblastic Leukemia (ALL) – 1 in 5 are due to genes mutated by chemotherapy – Nov 2019 10 Nov, 2019
Childhood Cancer survivors – only 1 in 25 had consumed Vitamin D RDA – Oct 2019 22 Oct, 2019
Children with cancer were deficient in Vitamin D, Vitamin C, and Zinc – July 2019 10 Jul, 2019
Childhood cancer survivors have increased chronic health problems as adults – Sept 2017 13 Oct, 2017
Children with Cancer were 3X more likely to be vitamin D deficient – July 2013 05 Jan, 2014
Vitamin D levels very low for some childhood cancers, then got lower – Sept 2012 29 Sep, 2012

Some health problems recur if low vitamin D


A health problem associated with low D is often associated with other low D problems (if not supplement)

Diseases that may be related via low vitamin D here is a portion of a long list
88+ Disease associations:   Disease 1 ==> Disease 2 (both associated with low vitamin D


Note: Some health problems protect themselves by deactivating the Vitamin D Receptor

Cancer removal does not reactivate the Vitamin D Receptor
A deactivated VDR results in less Vitamin D getting to cells
Which results in more health problems in the future, even if vitamin D levels are raised to 30 ng by supplementation


See also in VitaminDWiki


Created by admin. Last Modification: Friday November 25, 2022 17:39:00 GMT-0000 by admin. (Version 10)

Attached files

ID Name Comment Uploaded Size Downloads
18855 Childhood Cancer.jpg admin 25 Nov, 2022 41.78 Kb 174
18853 Chilhood cancer recurr.pdf admin 25 Nov, 2022 261.43 Kb 131