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Vitamin D helps some child health problems in Pakistan – May 2022

Adjunctive vitamin D therapy in various diseases in children: a scenario according to standard guideline

BMC Pediatrics volume 22, https://doi.org/10.1186/s12887-022-03297-z
Hafsa Arshad, Faiz Ullah Khan, Naveed Ahmed, Naveed Anwer, Ali Hassan Gillani & Asim.ur. Rehman



Strange, no enties between 1,000 IU to 200,000 IU
Adherence to standard guidelines is imperative when question comes to disease management. The present study aimed to evaluate the administration of adjunctive vitamin D therapy in various diseases, its adherence to standard guideline and the effect of socioeconomic status on the consumption of vitamin D in children.

Cross sectional observational study was conducted among 400 ambulatory pediatric patients at Children’s Hospital, Pakistan Institute of Medical Sciences Islamabad, from November 2017 to June 2018. Data were collected by a self-designed structured questionnaire from the patient’s medical chart. Adjunctive vitamin D therapy adherence was evaluated by the U. S endocrinology clinical practice guideline of vitamin D deficiency. The association between socioeconomic status and consumption of vitamin D was examined by chi-square. Alpha value (p ≤ 0.005) was considered statistically significant. Statistical analysis was done by SPSS version 25.

In 400 patients, 9 diseases and 21 comorbid conditions were identified, in which adjunctive vitamin D therapy was prescribed. Adherence to vitamin D testing in high-risk vitamin D deficiency diseases as; seizures (3.8%), bone deformities (13.3%), steroid-resistant nephrotic syndrome (0.0%), cerebral palsy (5.9%) and meningitis (14.3%). Adherence to prescribed vitamin D dose was in (41.3%) patients in various diseases. Significant association (p < 0.05) was found between socioeconomic status and consumption of vitamin D in children and mothers.

It was found that adjunctive vitamin D was being prescribed in various diseases and comorbidities. Overall poor adherence to the standard guideline was observed in disease management in children. Low socioeconomic status affects vitamin D supplementation consumption in children.
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VitaminDWiki - Infant-Child category has 748 items and contains

Having a good level of vitamin D cuts in half the amount of:

Need even more IUs of vitamin D to get a good level if;

  • Have little vitamin D: premie, twin, mother did not get much sun access
  • Get little vitamin D: dark skin, little access to sun
  • Vitamin D is consumed faster than normal due to sickness
  • Older (need at least 100 IU/kilogram, far more if obese)
  • Not get any vitamin D from formula (breast fed) or (fortified) milk
    Note – formula does not even provide 400 IU of vitamin D daily

Infants-Children need Vitamin D

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17569 dose sizes.jpg admin 07 May, 2022 20:30 13.28 Kb 96
17568 Cormorbidities.jpg admin 07 May, 2022 20:30 149.72 Kb 100
17567 Guideline flow chart.jpg admin 07 May, 2022 20:29 94.88 Kb 133
17566 Adjunctive vitamin D therapy - children_CompressPdf.pdf PDF 2022 admin 07 May, 2022 20:03 530.94 Kb 60