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Vitamin D and diabetes – review with many charts and tables – March 2014

Endocrinol Metab Clin North Am. 2014 Mar;43(1):205-32. doi: 10.1016/j.ecl.2013.09.010. Epub 2013 Dec 12.
Mitri J1, Pittas AG2.
1Division of Endocrinology, Diabetes and Metabolism, Prima CARE Medical Center, 277 Pleasant Street, Fall River, MA 02721, USA. Electronic address: joannamitri at hotmail.com.
2Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.

Insulin secretion


Insulin action



There has been increasing evidence that vitamin D may have a role in modifying risk of diabetes. Vitamin D has both direct and indirect effects on various mechanisms related to the pathophysiology of type 2 diabetes, including pancreatic beta cell dysfunction, impaired insulin action and systemic inflammation. This article describes the biologic plausibility behind the potential association between vitamin D and type 2 diabetes and summarizes the current evidence from human studies that suggests but does not prove a relation between vitamin D and type 2 diabetes, and briefly reports on the potential association between vitamin D and type 1 diabetes.

PMID: 24582099

 Download the PDF from VitaminDWiki

See also VitaminDWiki

Overview Diabetes and vitamin D contains the following summary

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 477 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

  • Appears that >2,000 IU will Prevent
  • Appears that >4,000 IU will Treat , but not cure
  • Appears that Calcium and Magnesium are needed for both Prevention and Treatment
    • which are just some of the vitamin D cofactors

Number of articles in both categories of Diabetes and:

  • Dark Skin 23;   Intervention 51;   Meta-analysis 34;   Obesity 28;  Pregnancy 40;   T1 (child) 37;  Omega-3 11;  Vitamin D Receptor 21;  Genetics 11;  Magnesium 19    Click here to see details

Attached files

ID Name Comment Uploaded Size Downloads
6095 Insulin secretion.jpg admin 24 Oct, 2015 15:13 57.11 Kb 1495
6094 Diabetes risk.jpg admin 24 Oct, 2015 15:08 43.77 Kb 1110
6093 Insulin.jpg admin 24 Oct, 2015 15:08 20.34 Kb 1557
6092 Vitamin D and diabetes.pdf PDF 2014 admin 24 Oct, 2015 15:08 1.14 Mb 695
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