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Vitamin D (and VDR) – Vieth book chapter - 2017

Vitamin D

International Encyclopedia of Public Health (Second Edition) 2017, Pages 383–387; http://dx.doi.org/10.1016/B978-0-12-803678-5.00488-4
Reinhold Vieth


Blurry image from the free abstract

See also VitaminDWiki

Vitamin D Receptor category has the following

507 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

See also: 47 studies in the Resveratrol category

It appears that 30% of the population have a poor VDR (40% of the Obese )
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
- - - - - - - -
The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (19 studies), Breast Cancer (22 studies), Colon Cancer (13 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (24 studies), Hypertension (9 studies), Infant (21 studies), Lupus (6 studies), Metabolic Syndrome (4 studies), Mortality (4 studies), Multiple Sclerosis (12 studies), Obesity (16 studies), Pregnancy (24 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (35 studies),   Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation

55 health problems associated with poor VDR

A poor VDR is associated with the risk of 55 health problems  click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023  click here for details
Some health problem, such as Breast Cancer reduce the VDR

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR

How to increase VDR activation

Compensate for poor VDR by increasing one or more:

1) Vitamin D supplement  Sun
Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D Receptor
13) Sulfroaphane and perhaps sulfurVitamin D Receptor
14)Butyrate especially gutVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR

Vitamin D deficiency causes rickets in children and osteomalacia in adults, both of which are accompanied by muscle weakness. Deficiency is measureable by a blood test of the vitamin D metabolite, 25-hydroxyvitamin D [25(OH)D]. Disagreements about the need for vitamin D are based on differing opinions about desirable health-related thresholds for serum 25(OH)D.

Debates are also about how much extra vitamin D might be needed to sustain those thresholds and about whether health criteria in addition to the bone, muscle, pain, and falls are pertinent to establishing the desired 25(OH)D level. The Institutes of Medicine considers 25(OH)D levels below 50 nmol L-1 (20 ng mL-1) as undesirable, and in some countries, average ‘normal’ population levels are lower than that. Vitamin D is produced naturally in skin exposed to ultraviolet (UV)-B light.

Vitamin D is not produced in the skin covered by clothing or if the UV index is below 4
(i.e., if the angle of the sun is so low that a person's shadow is longer than his/her height).

Vitamin D is not naturally present in most foods, but public health advice to fortify food or to supplement with it remains controversial.

At latitudes south of 30 degrees, the most cost-effective approach is to recommend more exposure of the skin to sunshine, but that is complicated by local culture and worries about skin cancer.

Public health policies surrounding vitamin D and sun exposure remain unsettled.

Meanwhile, intense research interest in the field continues to produce provocative results.

Publisher wants $31.50 for the 4 pages

Vitamin D (and VDR) – Vieth book chapter - 2017        
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