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Calcium from plants might be OK – Dec 2016

A 7-Year Longitudinal Trial of the Safety and Efficacy of a Vitamin/Mineral Enhanced Plant-Sourced Calcium Supplement.

J Am Coll Nutr. 2016;35(2):91-9. doi: 10.1080/07315724.2015.1090357. Epub 2016 Feb 17.
Kaats GR 1, Preuss HG 2, Stohs S 3, Perricone N 4.
1a Integrative Health Technologies, Inc. , San Antonio , Texas (G.R.K.).
2b Department of Biochemistry , Georgetown University Medical Center , Washington , DC (H.G.P.).
3c Creighton University , Frisco , Texas (S.S.).
4d Transdermal Biotechnology, Inc. , Meriden , Connecticut (N.P.).


This study was probaby paid for by the manufacturer.
Most Calcium supplements result in poor health, especially when vitamin D is increased
A plant-based supplement with many Vitamin D cofactors is probably better than just Calcium supplements
Bone Mineral Density INCREASED by 7% in 7 years

The Magnesium, Vit D, Vit K, and Boron also help build bones,
and MAY reduce other problems
no consensus on Strontium

Note: Trial used 2 capsules taken twice a day - at a cost of $2.32
Competing products using very similar ingredients are about 1/4 that price

See also VitaminDWiki

See also web

  • https://www.algaecal.com derived from a marine algae, 2 caps twice a day with meals
    • vitamin D3, vitamin K2, boron, and additional magnesium have been added to the algae powder to make AlgaeCal Plus

See also Amazon (Jan 2018) - Vegan Calcium, Mg, Vit D, Vit K, and usually Boron, Silica, generally from algae

Note: the above are just a few of the products available which have enough quantity of ingredients to be useful.

 Download the PDF from VitaminDWiki

The objective of this study was to examine the safety and efficacy of a vitamin-mineral enhanced plant-sourced calcium AlgaeCal calcium (AC) in female consumers who had taken the supplement from 1 to 7 years.

Consumers who had completed at least one dual-energy x-ray absorptiometry (DEXA) bone mineral density (BMD) scan (N = 172) and/or blood chemistry test (N = 30) and purchased AC from 1 to 7 years were contacted and offered complimentary repeat tests. Safety and efficacy were examined by annualized changes in a 45-measurement blood chemistry panel and changes in BMD.

No adverse effects or safety concerns were found in any of the annualized within-group annualized changes in the 45 blood chemistries or in between-group changes in a similar control group (n = 5070) who completed the same measurements. With regard to BMD, consistent and statistically significant within-group increases were found for the 7-year study period and when compared to expected BMD changes in 3 large databases or the combination (N = 25,885) of the 3 databases. Data from this study suggest that AC supplement was associated with a significant annualized and linear increase in BMD of 1.04% per year, 7.3% over the 7-year study period. These results stand in marked contrast to normative or expected changes of -0.4%/y from 3 different databases or in a combination of all 3 databases (N = 16,289).

No evidence was found in cardiovascular risk as measured by adverse changes in blood lipids, nor was any evidence found of a diminished efficacy over the 7-year study period because gains in BMD were consistent and linear over the 7-year study period, averaging 1.04% per year over the 7-year study. The results are also consistent with earlier short-term studies suggesting that this supplement can facilitate significant increases in total body BMD in contrast to studies suggesting that calcium supplements can only slow down age-related declines in BMD.

PMID: 26885697 DOI: 10.1080/07315724.2015.1090357

Attached files

ID Name Comment Uploaded Size Downloads
7504 ingredients.jpg admin 16 Dec, 2016 23.61 Kb 1178
7502 AlgaeCal Plus ingredients.jpg admin 16 Dec, 2016 27.79 Kb 1562
7501 bone density vs year.jpeg admin 16 Dec, 2016 88.13 Kb 1355
7499 Plant-sourced Calcium.pdf admin 16 Dec, 2016 706.16 Kb 1115