Calcitriol (active Vitamin D) prevents and treats COVID (with Chronic Kidney Disease in this case) June 2022

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Vitamin D for Recovery of COVID-19 in Patients With Chronic Kidney Disease

Front. Nutr., 15 June 2022 https://doi.org/10.3389/fnut.2022.930176
Wen-Fang Chiang1,2,3, Po-Jen Hsiao1,2,3 and Jenq-Shyong Chan1,2,3*
1 Division of Nephrology, Department of Medicine, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan
2 Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
3 School of Medicine, National Defense Medical Center, Taipei, Taiwan

Table of Contents

Randomized Controlled Trials

The severity of coronavirus disease 2019 (COVID-19) is determined not only by viral damage to cells but also by the immune reaction in the host. In addition to therapeutic interventions that target the viral infection, immunoregulation may be helpful in the management of COVID-19. Vitamin D exerts effects on both innate and adaptive immunity and subsequently modulates immune responses to bacteria and viruses. Patients with chronic kidney disease (CKD) frequently have vitamin D deficiency and increased susceptibility to infection, suggesting a potential role of vitamin D in this vulnerable population. In this paper, we review the alterations of the immune system, the risk of COVID-19 infections and mechanisms of vitamin D action in the pathogenesis of COVID-19 in CKD patients. Previous studies have shown that vitamin D deficiency can affect the outcomes of COVID-19. Supplementing vitamin D during treatment may be protective against COVID-19. Future studies, including randomized control trials, are warranted to determine the effect of vitamin D supplementation on the recovery from COVID-19 in CKD patients.

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VitaminDWiki - 4 studies in both categories Calcitriol and Virus

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VitaminDWiki - 16 studies in both categories Calcitriol and Kidney

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VitaminDWiki - Calcitriol category CONTAINS

56 Calcitriol items in VitaminDWiki     See also: Calcidiol category listing which has 46 items

Many ways to increase Vitamin D - click on chart for details

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VitaminDWiki - Chronic Kidney Disease needs Vitamin D: how much, what kind - many studies