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4 weeks of Omega-3 better than 2 week 800 calorie diet before Bariatric Surgery – RCT March 2019

Four Weeks of Preoperative Omega-3 Fatty Acids Reduce Liver Volume: a Randomised Controlled Trial

OBES SURG (2019). https://doi.org/10.1007/s11695-019-03814-7
Nathalie Bakker, Rick S. van den Helder Remy W. F. Geenen Michiel A. Hunfeld Huib A. Cense Ahmet Demirkiran Alexander P. J. Houdijk

VitaminDWiki

Founder of VitaminDWiki speculates that Omega-3 + Vitamin D would be great before Bariatric Surgery


Items in both categories Obesity and Omega-3 are listed here:

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Low Calorie Diet (LCD) was much harder on patients than Omgea-3
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Purpose
Weight loss before bariatric surgery with a low-calorie diet (LCD) has several advantages, including reduction of liver volume and an improved access to the lesser sac. Disadvantages include performing surgery in a state of undernutrition, side effects, costs and patient compliance. Omega-3 fatty acids may serve as an alternative to reduce liver steatosis.

Materials and Methods
A randomised controlled open-label trial was done to compare the effects of a LCD with Modifast (800 kcal/day) during 2 weeks with 2 g of omega-3 fatty acids a day and a normal diet (2000 kcal/day) during 4 weeks. Total liver volume (TLV) and volume of the left liver lobe (LLL), visceral fat area (VFA) and muscle area (SMA) at the L3–L4 level were measured with MRI before and after preoperative treatment.

Results
Sixty-two morbidly obese women undergoing laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) were recruited. In both groups, there was a significant decrease in LLL, TLV and VFA. For LLL and TLV reduction, the LCD had a significantly larger effect (p < 0.05). Only in the LCD group was there a significant decrease in SMA with significantly more side effects and worse compliance.

Conclusion
Both the LCD and omega-3 diet reduced LLL, TLV and VFA. The LCD outperformed the omega-3 diet in LLL and TLV reduction, but induced significant loss of SMA and had worse compliance due to more side effects. Omega-3 fatty acids may provide a safe and more patient-friendly alternative for a LCD and further research is indicated.

Created by admin. Last Modification: Saturday March 23, 2019 15:26:20 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
11647 Diet vs Omega-3.jpg admin 23 Mar, 2019 15:11 28.63 Kb 92
11646 Omega-3 liver size.pdf PDF 2019 admin 23 Mar, 2019 15:11 1.80 Mb 43
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