Loading...
 
Translate Register Log In Login with facebookLogin and Register

26 X increase in Vitamin D prescriptions for youths in England in 8 years – Dec 2019

Vitamin D prescribing in children in UK primary care practices: a population-based cohort study

Paediatrics http://dx.doi.org/10.1136/bmjopen-2019-031870
Mandy Wan1,2, Laura J Horsfall3, Emre Basatemur4, Jignesh Prakash Patel2,5, Rukshana Shroff6, Greta Rait3

 Download the PDF from VitaminDWiki
Image
Image

Vitamin D Levels After 6 months
Image

Objective To examine temporal changes in the incidence and patterns of vitamin D supplementation prescribing by general practitioners (GPs) between 2008 and 2016.

Design Population-based cohort study.

Setting UK general practice health records from The Health Improvement Network.

Participants Children aged 0 to 17 years who were registered with their general practices for at least 3 months.

Outcome measures Annual incidence rates of vitamin D prescriptions were calculated, and rate ratios were estimated using multivariable Poisson regression to explore differences by sociodemographic factors. Data on the type of supplementation, dose, dosing schedule, linked 25-hydroxyvitamin D (25(OH)D) laboratory test results and clinical symptoms suggestive of vitamin D deficiency were analysed.

Results Among 2 million children, the crude annual incidence of vitamin D prescribing increased by 26-fold between 2008 and 2016 rising from 10.8 (95% CI: 8.9 to 13.1) to 276.8 (95% CI: 264.3 to 289.9) per 100 000 person-years. Older children, non-white ethnicity and general practices in England (compared with Wales/Scotland/Northern Ireland) were independently associated with higher rates of prescribing. Analyses of incident prescriptions showed inconsistent supplementation regimens with an absence of pre-supplementation 25(OH)D concentrations in 28.7% to 56.4% of prescriptions annually. There was an increasing trend in prescribing at pharmacological doses irrespective of 25(OH)D concentrations, deviating in part from UK recommendations. Prescribing at pharmacological doses for children with deficient status increased from 3.8% to 79.4%, but the rise was also observed in children for whom guidelines recommended prevention doses (0% to 53%). Vitamin D supplementation at pharmacological doses was also prescribed in at least 40% of children with no pre-supplementation 25(OH)D concentrations annually.

Conclusions There has been a marked and sustained increase in vitamin D supplementation prescribing in children in UK primary care. Our data suggests that national guidelines on vitamin D supplementation for children are not consistently followed by GPs.

Created by admin. Last Modification: Monday December 16, 2019 16:54:07 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
13096 England 6 month.jpg admin 05 Dec, 2019 02:56 52.25 Kb 25
13095 England 12-17.jpg admin 05 Dec, 2019 02:55 62.06 Kb 20
13094 England A.jpg admin 05 Dec, 2019 02:55 44.94 Kb 21
13093 England 26X.pdf admin 05 Dec, 2019 02:54 858.70 Kb 25
See any problem with this page? Report it (FINALLY WORKS)