Critically ill trauma patients - virtually none had even 30 ng of Vitamin D - Dec 2023

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Does Serum Vitamin D Influence the Prognosis of Critically Ill Patients with Trauma? A Prospective, Observational Study in a Trauma Center

Clin Orthop Surg v.15(6); 2023 Dec doi: 10.4055/cios23168
Yong-Cheol Yoon, MD, Won-Tae Cho, MD,* Jin Yeong Jeon, MD,* and Hyung Keun Song,

Background
Vitamin D concentrations are associated with sepsis, pneumonia, and mortality in critically ill patients. However, the role of vitamin D in critically injured patients with trauma remains unknown. This study investigated the effects of vitamin D concentrations on outcomes in critically injured patients with trauma.

Methods
A prospective observational study was conducted by randomly selecting 100 patients among those who visited our trauma center. The serum vitamin D concentration was measured upon arrival at the hospital, and the length of stay in a trauma intensive care unit after admission, duration of mechanical ventilation, number of days spent in the hospital, development of complications, and death were investigated. The association between the surveyed variables and vitamin D concentrations was investigated using regression analysis.

Results
Of the 100 patients, 69 were men and 31 were women with an average age of 51.7 years. The average intensive care unit stay length was 18.4 days, and 6 patients (5.9%) died. Univariate regression analysis showed that the factors affecting patient mortality were age (p = 0.02), volume of blood transfused within 24 hours of arrival (p = 0.009), systolic blood pressure measured upon hospital arrival (p = 0.01), and serum lactate concentration measured upon hospital arrival (p = 0.03). Multivariate regression analysis showed that the factors affecting patient mortality were age (p = 0.01), volume of blood transfusion (p = 0.04), and systolic blood pressure measured upon hospital arrival (p = 0.01).

Conclusions
There were no statistically significant effects of serum vitamin D concentrations in critically ill patients with trauma on death during hospitalization.
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VitaminDWiki – Trauma and surgery category contains:

Trauma and Surgery category has 352 articles

Large dose Vitamin D before surgery was found to help by 35 studies
Vitamin D is needed before most surgeries – many studies and RCTs
4.8 X more likely to die within 28 days of ICU if low Vitamin D - Jan 2024
Sepsis is both prevented and treated by Vitamin D - many studies
Thyroidectomy and Vitamin D - many studies
Orthopaedic surgeries need Vitamin D – many studies
Cancer - After diagnosis   chemotherapy
TBI OR "Traumatic Brain Injury - 21 in title as of Sept 2022
Superbug (Clostridium difficile) Infections strongly associated with low vitamin D - many studies
Glutamine and Omega-3 have also been proven to help several traumas/surgeries
   Note: Vitamin D also prevents the need for various surgeries and Omega-3 prevents many concussions/TBI
Trauma and Surgery is associated with 22 other VitaminDWiki categories
  Such as loading dose 33, Mortality 23, Infant-Child 21 Intervention 19 Cardiovascular 13, Injection 13 in Sept 2022

Did you know?

• You can easily improve outcomes of many planned surgeries by increasing vitamin D ahead of time
  • Cancer surgery is the only known exception - extra Vitamin D is OK only if doctor reduces the chemo doses
• A loading dose of Vitamin D also improves unplanned hospital admissions
• Improvements include
  • Shorter recovery time
  • Shorter ICU time
  • Reduced deaths – in hospital, next month, next year
  • Reduced Sepsis = blood poisoning = infection