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Rationale and Plan for Vitamin D Food Fortification - July 2018

Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper

published: 17 July 2018 doi: 10.3389/fendo.2018.00373

Risk of Death (for any reason)

    Chart adapted from Much more likely to live longer if higher vitamin D – 27,000 seniors Feb 2017
Chart fails to consider increased deaths if raise vitamin D but not adjust cofactors
such as too much Calcium and to little Magnesium due to increased Vitamin D,
The excess Calcium is then deposited in arteries, muscles, heart organs, etc.
There might be no increased death rate for higher vitamin D levels if the cofactors were also adjusted

Authors: Piiz S, Marz W, Cashman KD, KieiyME, Whiting SJ, Hoick MF, Grant WB, Piudowski P Hiiigsmann M, Trummer C, Schwetz V, Lerchbaum E, Pandis M, Tomaschitz A, Grubier MR, Gaksch M, Verheyen N, Hoiiis BW, Rejnmark L, Karras SN, Hahn A, Bischoff-Ferrari HA, Reichrath J, Jorde R, Eimadfa I, Vieth R, Scragg R, Caivo MS, van Schoor NM, Bouiiion R, Lips P, Itkonen ST, Martineau AR, Lamberg-Aiiardt C and Zittermann A   Draft authors are bolded

Vitamin D deficiency can lead to musculoskeletal diseases such as rickets and osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such as respiratory tract infections, asthma exacerbations, pregnancy complications and premature deaths. Vitamin D has a unique metabolism as it is mainly obtained through synthesis in the skin under the influence of sunlight (i.e., ultraviolet-B radiation) whereas intake by nutrition traditionally plays a relatively minor role. Dietary guidelines for vitamin D are based on a consensus that serum 25-hydroxyvitamin D (25OHD) concentrations are used to assess vitamin D status, with the recommended target concentrations ranging from >25 to >50 nmol/L (>10->20ng/mL), corresponding to a daily vitamin D intake of 10 to 20 microgram (400-800 international units). Most populations fail to meet these recommended dietary vitamin D requirements. In Europe, 25(OH)D concentrations <30 nmol/L (12ng/mL) and <50 nmol/L (20ng/mL) are present in 13.0 and 40.4% of the general population, respectively. This substantial gap between officially recommended dietary reference intakes for vitamin D and the high prevalence of vitamin D deficiency in the general population requires action from health authorities. Promotion of a healthier lifestyle with more outdoor activities and optimal nutrition are definitely warranted but will not erase vitamin D deficiency and must, in the case of sunlight exposure, be well balanced with regard to potential adverse effects such as skin cancer. Intake of vitamin D supplements is limited by relatively poor adherence (in particular in individuals with low-socioeconomic status) and potential for overdosing. Systematic vitamin D food fortification is, however, an effective approach to improve vitamin D status in the general population, and this has already been introduced by countries such as the US, Canada, India, and Finland. Recent advances in our knowledge on the safety of vitamin D treatment, the dose-response relationship of vitamin D intake and 25(OH)D levels, as well as data on the effectiveness of vitamin D fortification in countries such as Finland provide a solid basis to introduce and modify vitamin D food fortification in order to improve public health with this likewise cost-effective approach.


Seems like there is very little room for fortification.
1,000 IU/day helps a few people get to 30 ng
However, governments continue to wrongly believe that 4,000 IU can be toxic
A person could easily consume 4X of the consumed fortified food
Finland, for one, had decided on fortification with 2,000 IU
This study has not even started to choose a dose range nor what food to fortify

 Download the PDF from VitaminDWiki

Created by admin. Last Modification: Tuesday July 17, 2018 20:16:48 GMT-0000 by admin. (Version 17)

Attached files

ID Name Comment Uploaded Size Downloads
10203 upper limit 4,000 IU.jpg admin 17 Jul, 2018 19:56 33.03 Kb 302
10202 Rationale and Plan for Vitamin D Food Fortification.pdf PDF 2018 admin 17 Jul, 2018 19:41 1.31 Mb 545
10063 HR fortification.jpg admin 30 Jun, 2018 16:45 24.66 Kb 675
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