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Chronic Kidney Disease patients need more than 20 ng of Vitamin D – workshop conclusion Oct 2018

The Role of Vitamin D in CKD Stages 3 to 4: Report of a Scientific Workshop Sponsored by the National Kidney Foundation

American Journal of Kidney Diseases, online 5 October 2018, https://doi.org/10.1053/j.ajkd.2018.06.031
Michal L.Melamed 1 Michel Chonchol2 Orlando M.Gutiérrez3 Kamyar Kalantar-Zadeh4 Jessica Kendrick 2 Keith Norris 5 Julia J.Scialla 6 Ravi Thadhani 78


More than 30 ng of vitamin D is sometimes needed (Kidney needs 50 ng) – March 2019

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Overview Kidney and vitamin D contains the following summary

Deficiency of 25-hydroxyvitamin D (25[OH]D) is common in patients with chronic kidney disease stages 3 and 4 and is associated with poor outcomes. However, the evaluation and management of vitamin D deficiency in nephrology remains controversial. This article reports on the proceedings from a “controversies conference” on vitamin D in chronic kidney disease that was sponsored by the National Kidney Foundation.
The report outlines the deliberations of the 3 work groups that participated in the conference. Until newer measurement methods are widely used, the panel agreed that clinicians should classify 25(OH)D “adequacy” as concentrations > 20 ng/mL without evidence of counter-regulatory hormone activity (ie, elevated parathyroid hormone).
The panel also agreed that 25(OH)D concentrations < 15 ng/mL should be treated irrespective of parathyroid hormone level. Patients with 25(OH)D concentrations between 15 and 20 ng/mL may not require treatment if there is no evidence of counter-regulatory hormone activity.
The panel agreed that nutritional vitamin D (cholecalciferol, ergocalciferol, or calcifediol) should be supplemented before giving activated vitamin D compounds. The compounds need further study evaluating important outcomes that observational studies have linked to low 25(OH)D levels, such as progression to end-stage kidney disease, infections, fracture rates, hospitalizations, and all-cause mortality. We urge further research funding in this field.

Created by admin. Last Modification: Sunday November 3, 2019 23:15:17 GMT-0000 by admin. (Version 3)