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Hypothesis – Optimize vitamin D at home by measuring excess Calcium in urine

It is difficult to determine how much vitamin D an individual needs

Need to add vitamin D for each of the following reasons

IU of vitamin D to add vs X

Even within the same risk group the vitamin D needed will vary by 4X

According to Dr. Vieth - May 2011 (see charts below) the body starts dumping calcium via the urine long before serum levels of calcium become elevated.

Hypothesis: The body starts exponentially dumping calcium via the urine would at the top of the personal optimal serum vitamin D range.
Thus we can interpret the urine dump of calcium as a precursor to the optimal D range.

Calcium increases in urine before increasing in blood if too much vitamin D - Veith

on wikipage = http://www.vitamindwiki.com/tiki-index.php?page_id=1660

Calcium/Creatinine ratio in urine vs vitamin D - Veith

in wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=1660

Hypothesis assumes that an individual will not have so much vertical variability

No increase in Calcium in Urine for vitamin D between 30 ng and 80 ng – July 2011

Urinary calcium response to high dose vitamin D3 with calcium supplementation in patients with multiple sclerosis.
Clin Biochem. 2011 Jul;44(10-11):930-2. Epub 2011 May 5.
Kimball SM, Burton JM, O'Connor PG, Vieth R.
University of Toronto, Department of Nutritional Sciences and Mount Sinai Hospital, Department of Pathology & Laboratory Medicine, Toronto, ON, Canada M5G 1X5. samantha.kimball at utoronto.ca

OBJECTIVE:To characterize the effect of vitamin D(3) intake on urinary calcium:creatinine ratios across predefined ranges of serum 25(OH)D.

DESIGN:Patients with multiple sclerosis (n=25) received escalating doses of vitamin D(3) (4000-40,000IU/d) with calcium (1200mg/d).

RESULTS: Urinary calcium:creatinine was driven by increased 25(OH)D when concentrations were <75nmol/L (r=0.424, p=0.009) and >200nmol/L (r=0.281, p=0.01), but no relationship existed when 25(OH)D concentrations were 76-200nmol/L.

CONCLUSIONS: A "safe", physiological range of 25(OH)D concentrations is 75-200nmol/L.

Copyright © 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved. PMID: 21570386

Low-cost test for Calcium in the urine

Sulkowitch Urine (Calcium) Test – see attached PDF – very low cost ($1.30 per test) and can do at home

10 tests for $10 + shipping most anywhere in the world

Test is very simple - but will have to guess conversion between units on the graph and turbidity

See also VitaminDWiki

Short url = http://is.gd/vitDCa

Attached files

ID Name Comment Uploaded Size Downloads
545 calcium test.jpg admin 31 May, 2011 34.43 Kb 6165
544 Test for Calcium in urine.pdf admin 31 May, 2011 79.04 Kb 13380