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Vitamin D in Critical care – they agree that 800 IU can be used (far too little) – July 2021

Vitamin D in critical care: where are we now and what is next?

Current Opinion in Critical Care: Aug 2021 - Vol 27 - Issue 4 - p 378-384, doi: 10.1097/MCC.0000000000000849
Amrein, Karina; Hoffmann, Magdalenaa,b; Lobmeyr, Elisabethc; Martucci, Gennarod


Many doctors do not prescribe enough to make a difference

The items which are in both Intervention and Trauma/Surgery are listed here

PDF is behind a paywall
Purpose of review
To summarize the recent evidence on the role of vitamin D deficiency in critically ill patients and emerging data claiming a role of vitamin D in COVID-19.

Recent findings
Vitamin D is a strong predictor for worse outcomes in critically ill patients, and as well in COVID-19. The vitamin D content in typical nutrition regimes is lower than what is recommended for the general population. Although its supplementation has been shown to reduce respiratory tract infections, asthma exacerbations and mortality risk in noncritically ill patients, its role in the acute setting is not yet clear. Several small intervention trials have shown interesting results in COVID-19, and larger studies are ongoing.

Although research on this topic is still ongoing, it appears reasonable to recommend at least the standard vitamin dose for the healthy population (600 - 800 IU of native vitamin D3). Many questions remain on the actual role, the best metabolite, regime, and so forth. However, the role for vitamin D in bone health is clear. Elderly ICU survivors have a high risk for osteoporosis/fractures, so at least in this population, an optimal vitamin D status should be targeted.

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