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Glyphosate (Roundup) increases risk of NH lymphoma by 41 percent – meta-analysis July 2019

Exposure to glyphosate-based herbicides and risk for non-Hodgkin lymphoma: A meta-analysis and supporting evidence

Reviews in Mutation Research, Vol 781, July–Sept. 2019, Pages 186-206 https://doi.org/10.1016/j.mrrev.2019.02.001
LuopingZhangaIemaanRanaaRachel M.ShafferbEmanuelaTaiolicLianneSheppardbd


Glyphosate and Vitamin D - many studies category starts with

  • There are 26 items in Glyphosate category in VitaminDWiki
  • Glyphosate [glahy-fos-eyt] is associated with many health problems
  • Glyphosate reduces Vitamin D by both reducing CYP27A1 gene + many minerals needed by Vit. D
    VitaminDWiki suspects that Glyphosate is responsible for 10-20% of the decreased Vitamin D getting to cells
  • Glyphosate is the only acknowledged active component of Roundup
    • However, Roundup is actually 125X more deadly to human cells than Glyphosate
  • Many countries now ban Glyphosate
  • Some bio-fuels for airplanes, trucks, and autos contain glyphosate
  • A crop can be called organic even if Roundup was used to dry it
        wheat, oats, beans, lentil, sunflower, soy, rapeseed oil, etc
  • You can compensate for Glyphosate by increasing your intake of
       Vitamin D, Magnesium, Boron, and Omega-3

 Download the PDF from Sci-Hub via VitaminDWiki

Glyphosate is the most widely used broad-spectrum systemic herbicide in the world. Recent evaluations of the carcinogenic potential of glyphosate-based herbicides (GBHs) by various regional, national, and international agencies have engendered controversy. We investigated whether there was an association between high cumulative exposures to GBHs and increased risk of non-Hodgkin lymphoma (NHL) in humans. We conducted a new meta-analysis that includes the most recent update of the Agricultural Health Study (AHS) cohort published in 2018 along with five case-control studies. Using the highest exposure groups when available in each study, we report the overall meta-relative risk (meta-RR) of NHL in GBH-exposed individuals was increased by 41% (meta-RR = 1.41, 95% confidence interval, CI: 1.13–1.75). For comparison, we also performed a secondary meta-analysis using high-exposure groups with the earlier AHS (2005), and we calculated a meta-RR for NHL of 1.45 (95% CI: 1.11–1.91), which was higher than the meta-RRs reported previously. Multiple sensitivity tests conducted to assess the validity of our findings did not reveal meaningful differences from our primary estimated meta-RR. To contextualize our findings of an increased NHL risk in individuals with high GBH exposure, we reviewed publicly available animal and mechanistic studies related to lymphoma. We documented further support from studies of malignant lymphoma incidence in mice treated with pure glyphosate, as well as potential links between glyphosate / GBH exposure and immunosuppression, endocrine disruption, and genetic alterations that are commonly associated with NHL or lymphomagenesis. Overall, in accordance with findings from experimental animal and mechanistic studies, our current meta-analysis of human epidemiological studies suggests a compelling link between exposures to GBHs and increased risk for NHL.

Created by admin. Last Modification: Thursday January 9, 2020 15:14:30 GMT-0000 by admin. (Version 4)

Attached files

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13303 Glyphosate timeline.jpg admin 09 Jan, 2020 15:02 231.08 Kb 267
13302 Gly lynphoma.pdf PDF 2019 admin 09 Jan, 2020 15:01 2.83 Mb 390