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Vitamin D might reduce Multisystem Inflammatory Syndrome in children – March 2021

Front Immunol. 2021 Mar 8;12:648546. doi: 10.3389/fimmu.2021.648546
Gavriela Feketea 1 2, Vasiliki Vlacha 3, Ioana Corina Bocsan 4, Emilia Vassilopoulou 5, Luminita Aurelia Stanciu 6, Mihnea Zdrenghea 1 7

VitaminDWiki

Also known as Paediatric Inflammatory Multisystem Syndrome
Is apparently similar to Kawasaki disease


See also web

  • "Multisystem inflammatory syndrome in a neonate, temporally associated with prenatal exposure to SARS-CoV-2: a case report - April 1. 2021 PDF
  • "COVID‐19 multisystem inflammatory syndrome in three teenagers with confirmed SARS‐CoV‐2 infection"- July 2020 PDF

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Multisystem Inflammatory Syndrome in children (MIS-C) is a rare but devastating complication of coronavirus disease 19 (COVID-19). The development of prognostic biomarkers and more importantly the implementation of new treatment modalities would have a significant impact in clinical practice regarding the outcome of MIS-C. Vitamin D could be a potential candidate. In this mini review we analyze the immunomodulatory role of vitamin D in viral infections and specifically in COVID-19. We also examine the current literature regarding the association of vitamin D with MIS-C and Kawasaki disease. The vitamin D was evaluated not only as a biomarker but also as a nutritional supplement.

We concluded that vitamin D levels could be valuable in predicting severe forms of MIS-C and correction of abnormal levels in severe MIS-C may influences its evolution. 25-hydroxyvitamin D3 [25(OH)D3] supplementation raising serum [25(OH)D] concentrations potentially have a favorable effect in reducing the severity of MIS-C in certain circumstances. Further studies are needed to confirm these results.


Created by admin. Last Modification: Thursday March 25, 2021 23:26:50 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
15319 COVID‐19 multisystem inflammatory syndrome in three teenagers_compressed.pdf PDF 2020 admin 25 Mar, 2021 23:23 208.17 Kb 8
15318 MIS April 1.pdf PDF 2021 admin 25 Mar, 2021 23:17 1.85 Mb 8
15317 MIS-C.jpg admin 25 Mar, 2021 23:05 54.53 Kb 42
15316 Multisystem Inflammatory Syndrome vitamin D COVID.pdf PDF 2021 admin 25 Mar, 2021 23:05 356.83 Kb 11
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