Toggle Health Problems and D

Vitamin D is the most common nutritional deficiency worldwide – Best Practice BMJ Dec 2012

Lots of information

Apparently anyone can sign up for a 7 day free trial to access the following


  • The most common nutritional deficiency worldwide, characterised by serum 25-hydroxyvitamin D <50 nanomol/L (<20 nanograms/mL). Vitamin D insufficiency is regarded as a serum 25-hydroxyvitamin D level between 51 and 72 nanomol/L (21 and 29 nanograms/mL).
  • Main causes include sun avoidance, using sun protection, increased skin pigmentation, inadequate dietary and supplemental vitamin D intake, malabsorption syndromes, obesity, and medication use.
  • Acquired and inherited disorders that either reduce or prevent the metabolism of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D also present with biochemical and skeletal abnormalities seen with vitamin D deficiency, but in a more severe form.
  • Most patients are asymptomatic. Severe, prolonged vitamin D deficiency causes growth retardation and rickets in children and osteomalacia, osteopenia, and osteoporosis in adults.
  • Both vitamin D deficiency and vitamin D insufficiency are corrected by giving vitamin D2 or vitamin D3 in treatment doses followed by lifelong maintenance doses; adequate, sensible sunlight exposure should be encouraged.
  • Additional replacement with 1,25-dihydroxyvitamin D or one of its active analogues is necessary for those with disorders of vitamin D metabolism.

Attached files

ID Name Comment Uploaded Size Downloads
1858 Best Practice.jpg admin 20 Dec, 2012 14:30 29.29 Kb 1160
See any problem with this page? Report it (WORKS NOV 2021)