Toggle Health Problems and D

Metabolic syndrome is associated with vitamin D independently of obesity – 2012

The association of hypovitaminosis d with the metabolic syndrome is independent of the degree of obesity.

ISRN Endocrinol. 2012;2012:691803. doi: 10.5402/2012/691803. Epub 2012 Oct 24.
Miñambres I, Sánchez-Hernández J, Sánchez-Quesada JL, Rodríguez J, de Leiva A, Pérez A.

Endocrinology and Nutrition Department, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain ; Medicine Department, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.

Background. It remains uncertain whether the metabolic syndrome (MS) or insulin resistance contribute to the association between vitamin D deficiency and obesity.

Methods. We conducted a cross-sectional survey of 343 subjects who were overweight or obese. We analyzed anthropometric data and the presence or absence of MS. Additionally, we determined 25-hydroxyvitamin D (25OHD) and insulin concentrations, and the HOMA index was calculated. Chi-square test,Mann-Whitney U test, Student's t-tests,and logistic regression analysis were used.

Results. The mean age of the patients was 42 ± 11 years, and 65.9% were women. The mean BMI was 34.7 ± 8.3 kg/m(2) and 25(OH)D levels were 53.7 ± 29.8 nmol/L. Forty-six patients (13.4%) had MS. Vitamin D status was associated with the degree of obesity, especially with a BMI > 40 kg/m(2). Patients with MS had lower levels of 25(OH)D than patients without (43.3 ± 29.0 versus 55.3 ± 29.6 mmol/L, resp.), and the odds ratio for hypovitaminosis D was 2.7 (confidence interval (CI), 1.14-6.4) (P = .023) for patients with MS versus patients without MS, irrespective of the degree of obesity.

Conclusions. Our data confirm the association between vitamin D and MS and suggest that this association is independent of the degree of obesity.

PMID: 23150833

PDF is attached at the bottom of this page

See also VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
2809 Metabolic not obesity.pdf PDF admin 14 Jul, 2013 22:04 479.74 Kb 840
See any problem with this page? Report it (WORKS NOV 2021)