Prevalence and risk factors of myopia in adult Korean population: Korea national health and nutrition examination survey 2013-2014 (KNHANES VI).
PLoS One. 2019 Jan 24;14(1):e0211204. doi: 10.1371/journal.pone.0211204. eCollection 2019.
Han SB1, Jang J2, Yang HK3, Hwang JM3, Park SK2.
- Myopia in adults is 8 percent more likely for every 4 ng less Vitamin D – meta-analysis July 2018
- Myopia, dry eye and Vitamin D – PhD 2017
- More sun when young, less myopia when old – Jan 2017
- Less myopia associated with work outdoors, less education, higher Vitamin D, higher lutein – Dec 2016
- Myopia 2 times more likely if Vitamin D Receptor problem – June 2011
PURPOSE: To evaluate the prevalence and risk factors of myopia in adult Korean population.
Population-based cross-sectional data of 3,398 subjects aged 19 to 49 years was obtained using the Korea National Health and Nutrition Examination Survey 2013-2014 (KNHANES VI). Data, including refractive errors and potential risk factors were analyzed. The prevalence and risk factors of myopia, low myopia, and high myopia-defined as a spherical equivalent (SEQ) ≤ -0.5 diopters (D), -6.0 D < SEQ <-0.5 D, and SEQ ≤ -6.0 D, respectively-were evaluated.
The prevalence of myopia and high myopia were 70.6 (standard error (SE), ±1.1)% and 8.0 (SE, ±0.6)%, respectively. In multivariable analysis, younger age, higher education (≥12 years), parental myopia, lower serum 25-hydroxyvitamin D (25(OH)D) concentration (<9 ng/mL), longer time spent on near work (≥3 hours/day), and higher white blood cell (WBC) count (5-8.9 x 103) were associated with increased prevalence of both myopia and high myopia. Serum 25(OH)D concentration of ≥ 9 ng/ml was significantly associated with decreased prevalence of high myopia in participants with near work of ≥3 hours/day, although the effect was not significant in myopia and low myopia.
CONCLUSIONS: The prevalence of myopia and high myopia in Korean adults was substantially high, which increased with decreasing age. In addition to parental myopia, the serum 25(OH)D concentration, near work and inflammation reflected by WBC counts may be associated with myopia.
PMID: 30677087 DOI: 10.1371/journal.pone.0211204