Medicine (Baltimore). 2021 Jul 2;100(26):e26570. doi: 10.1097/MD.0000000000026570.
Fan Gao 1, Peng Li 2, Ya-Qian Liu 3, Yan Chen 2
Vision category starts with the following
- Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019
- Vitamin D treats and prevents a variety of eye problems (need 70 ng) – June 2018
- Vitamin D and Myopia, AMD, Diabetic Retinopathy, Uveitis, Glaucoma, VDR etc. – May 2015
- Myopia may be related to low vitamin D
- VitaminDWiki pages with MYOPIA in title (16 as of June 2021)
- Tears often have 25 % higher levels of vitamin D than does blood
- Cataracts prevented and perhaps treated by Vitamin D - 2015
- All people with Cataracts had low vitamin D levels – April 2019
- Vitamin D and Age-Related Macular Degeneration (and 2 AMD meta-analyses) – Oct 2017
- Vitamin D is the best vitamin to fight glaucoma – May 2018
To analyze the serum 25 hydroxyvitamin D (25OHD) concentration in Chinese children with myopia and explore its correlation with myopia.From July to September in 2019, myopic children were collected from the Myopia Influencing Factors Survey Project. The basic information and vision related behaviors of the subjects were collected by questionnaire. The diopter of the children without dilated pupils was measured by the computerized refractometer. Meanwhile, 5 ml fasting venous blood samples were collected for the determination of serum 25(OH)D concentration. A total of 186 children were included in this study, including 90 males and 96 females, with an average age of 8 ± 3.26 years. The detection rate of serum 25(OH)D deficiency in myopic children was 65.59% (122/186). There was statistical significance in the detection rate of serum 25(OH)D deficiency in children with different myopic degrees (χ2 = 6.635, P = .010).
The average serum 25(OH)D concentration in myopic children was 14.86 (10.67-18.96) ng/ml, and the difference of serum 25(OH)D concentration in children with different myopia degrees was statistically significant (Z = 20.23, P < .001). Logistic regression analysis showed that after controlling for gender, parental myopia, after-school class, and outdoor activities, the prevalence of developing moderate and high myopia was 2.051 times (95% confidence interval: 1.272-3.724) higher in the serum 25(OH)D deficiency group than in the serum 25(OH)D sufficiency group. There is a positive correlation between serum 25(OH)D concentration and the equivalent spherical degree of myopic children. The study found that serum 25(OH)D concentration is closely related to the prevalence of myopia in Chinese children. The results further support the conclusion that children with a higher level of serum 25(OH)D have a lower prevalence of moderate to high myopia. The results of this study provide a basis for further research into the relationship between vitamin D and visual development in children and its mechanisms.
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