Venous ulcers 2X more likely if low level of vitamin D – Aug 2012

Vitamin D deficiency in patients with chronic venous ulcers.

Rev Col Bras Cir. 2012;39(1):60-3.
Burkievcz CJ, Skare TL, Malafaia O, Nassif PA, Ribas CS, Santos LR.
Faculdade Evangélica do Paraná, Hospital Universitário Evangélico de Curitiba, PR, Brasil. claudinejuliana at gmail.com

OBJECTIVE:
To study if the prevalence of vitamin D deficiency in patients with venous leg ulcer is higher than in the control population.

METHODS:
Serum levels of 25 hidroxi (OH)-vitamin D3 was studied by chemiluminescence in 27 patients with chronic venous ulcer and 58 controls at the Evangelical Hospital of Curitiba.

RESULTS:
The levels of 25 OH-vitamin D3 were below 8 ng/dl in 11.1% of ulcer patients and 3.4% of controls; between 8 and 20 ng/dl in 46.1% of ulcer patients and 25.8% of controls; between 21 and 30 ng/dl in 22.2% of ulcer patients and 27.5% of controls and above 30 ng/dl in 43.1% of controls and 18.5% of ulcer patients (p=0.04).

CONCLUSION:
There is an increased prevalence of vitamin D deficiency in patients with chronic venous leg ulcers.

PMID: 22481708

PDF is attached at the bottom of this page

Follow-up Random Controlled Trial by same authors

• Venous ulcers became much smaller with weekly 50000 IU vitamin D – RCT Oct 2012