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Children with severe caries were 2X more likely to have inadequate vitamin D – July 2012

The relationship between vitamin d and severe early childhood caries: a pilot study.

Int J Vitam Nutr Res. 2012 Jan;82(1):53-62.
Schroth R, Jeal N, Kliewer E, Sellers E.
University of Manitoba, Winnipeg, Manitoba, Canada, and Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada.

Introduction: Children with Severe Early Childhood Caries (S-ECC) routinely require dental surgery. S-ECC is known to affect childhood health and well-being. The objective of this pilot study was to assess vitamin D [25(OH)D] levels and determine whether differences exist between children with and without S-ECC.

Methods: During July-September 2008, children undergoing surgery for S-ECC < 72 months of age from southern Manitoba were recruited. Age-matched controls were caries-free. Parents completed an interviewed questionnaire. A serum sample was obtained for 25(OH)D and parathyroid hormone (PTH) levels. This study was approved by the University of Manitoba?s Ethics Board. Statistics included chi-square analysis, t-tests, and multiple and logistic regression. A p value of <= 0.05 was significant.

Results: Thirty-eight children participated (50 % with S-ECC). There was no significant age difference between groups (p = 0.82).

The majority of the entire sample (84.2 %) had inadequate vitamin D levels.

Children with S-ECC had lower concentrations of 25(OH)D (52.9 ± 15.1 nmol/L vs. 64.4 ± 21.3, p = 0.032) and were at twice the odds of having inadequate levels (<75 nmol/L). Children with S-ECC also had significantly higher PTH levels than caries-free children (53.5 ± 17.6 cm/L vs. 33.9 ± 12.9, p < 0.001). A greater number with S-ECC had elevated PTH levels (68.4 % vs. 21.1 %, p < 0.01).

Conclusions: This pilot study is the first to report differences in 25(OH)D between those with S-ECC and cavity-free controls. Children with S-ECC have lower vitamin D levels and increased PTH levels compared to age-matched controls.

PMID: 22811377
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Comment by VitaminDWiki

Vitamin D Cofactors such as Calcium, Magnesium, and Vitamin K2, are also very important in making bone and teeth.
Also helpful are elements which are non cofactors, such as Boron, Silicon, and Strontium

See also VitaminDWiki

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