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Pelvic floor disorder strongly associated with lower vitamin D – March 2012

Vitamin D status in women with pelvic floor disorder symptoms

Candace Y. Parker-Autry, Alayne D. Markland, Alicia C. Ballard, Deidra Downs-Gunn and Holly E. Richter
International Urogynecology Journal March 2012
DOI: 10.1007/s00192-012-1700-8

Introduction and hypothesis :Our aim was to characterize the relationship between 25-hydroxyvitamin D 25(OH)D status with pelvic floor symptom distress and impact on quality of life.

Methods: A retrospective chart review was performed in women with a 25(OH)D level drawn within 1 year of their gynecology/urogynecology visit. Validated questionnaires including the Colorectal–Anal Distress Inventory (CRADI)-8 and Incontinence Impact Questionnaire (IIQ-7) were used. Multivariate analyses characterized pelvic floor disorder (PFD) symptom differences among women by vitamin D status.

Results: We studied 394 women. Mean ± standard deviation (SD) 25(OH)D levels were higher in women without than with PFD symptoms (35.0?±?14.1 and 29.3?±?11.5 ng/ml, respectively (p?<?0.001)]. The prevalence of vitamin D insufficiency was 51% (136/268). CRADI-8 and IIQ-7 scores were higher among women with vitamin D insufficiency (p?=?0.03 and p?=?0.001, respectively). Higher IIQ-7 scores were independently associated with vitamin D insufficiency (p?<?0.001).

Conclusions: Insufficient vitamin D is associated with increased colorectal symptom distress and greater impact of urinary incontinence on quality of life.


PDF is attached at the bottom of this page

Women with symptoms 29 nanogram
Women without symptoms 35 nanograms


See also VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
2535 Pelvic Floor.pdf PDF admin 01 Jun, 2013 01:13 188.39 Kb 648
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