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Pelvic floor disorder strongly associated with lower vitamin D – March 2012

Vitamin D status in women with pelvic floor disorder symptoms

Candace Y. Parker-Autry, Alayne D. Markland, Alicia C. Ballard, Deidra Downs-Gunn and Holly E. Richter
International Urogynecology Journal March 2012
DOI: 10.1007/s00192-012-1700-8

Introduction and hypothesis :Our aim was to characterize the relationship between 25-hydroxyvitamin D 25(OH)D status with pelvic floor symptom distress and impact on quality of life.

Methods: A retrospective chart review was performed in women with a 25(OH)D level drawn within 1 year of their gynecology/urogynecology visit. Validated questionnaires including the Colorectal–Anal Distress Inventory (CRADI)-8 and Incontinence Impact Questionnaire (IIQ-7) were used. Multivariate analyses characterized pelvic floor disorder (PFD) symptom differences among women by vitamin D status.

Results: We studied 394 women. Mean ± standard deviation (SD) 25(OH)D levels were higher in women without than with PFD symptoms (35.0?±?14.1 and 29.3?±?11.5 ng/ml, respectively (p?<?0.001)]. The prevalence of vitamin D insufficiency was 51% (136/268). CRADI-8 and IIQ-7 scores were higher among women with vitamin D insufficiency (p?=?0.03 and p?=?0.001, respectively). Higher IIQ-7 scores were independently associated with vitamin D insufficiency (p?<?0.001).

Conclusions: Insufficient vitamin D is associated with increased colorectal symptom distress and greater impact of urinary incontinence on quality of life.

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Women with symptoms 29 nanogram
Women without symptoms 35 nanograms

See also VitaminDWiki

Attached files

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2535 Pelvic Floor.pdf PDF admin 01 Jun, 2013 01:13 188.39 Kb 986