Toggle Health Problems and D

ICU surgical patients with low vitamin D stayed longer and had more sepsis – Dec 2011

Effects of vitamin D deficiency in critically ill surgical patients

Presented at the 2011 annual meeting of the Midwest Surgical Association, Galena, Illinois.
The American Journal of Surgery; doi:10.1016/j.amjsurg.2011.09.012
Lisa Flynn M.D.a, Lisa Hall Zimmerman Pharm.D.b, Kelly McNorton Pharm.D.b, Mortimer Dolman M.D.c, James Tyburski M.D.a, Alfred Baylor M.D.a, Robert Wilson M.D.a, Heather Dolman M.D.a, hdolman at med.wayne.edu
a Department of Surgery, Wayne State University, School of Medicine, Detroit Receiving Hospital, Detroit Medical Center, Detroit, MI, USA
b Department of Pharmacy, Detroit Receiving Hospital, Detroit Medical Center, Detroit, MI, USA
c Department of Endocrinology, Mount Carmel East Hospital, Columbus, OH, USA
Received 25 July 2011; revised 25 September 2011; Available online 28 December 2011.

Background: The incidence of vitamin D deficiency in critically ill patients is reported to be up to 50%, with a 3-fold increase in predicted mortality, but limited data exist concerning vitamin D deficiency in critically ill surgical patients.

Methods Sixty-six adult surgical intensive care unit patients who had 25-hydroxyvitamin D serum levels evaluated from January 2010 to February 2011 were prospectively identified. Patients were divided into groups according to vitamin D level (<20 vs ?20 ng/mL).

Results Of the 66 patients evaluated, 49 (74%) had vitamin D levels < 20 ng/mL, and 17 (26%) had vitamin D levels >20 ng/mL.

Patients with vitamin D levels < 20 versus >20 ng/mL had longer lengths of hospital stay.
Lengths of intensive care unit stay were clinically longer, although not significant.
Infection rates tended to be higher (P = .09), and a higher incidence of sepsis was seen in the patients with vitamin D levels < 20 ng/mL.

Conclusions Vitamin D levels < 20 ng/mL have a significant impact on length of stay, organ dysfunction, and infection rates.
More data are needed on the value of supplementation to improve these outcomes.

PDF is attached at the bottom of this page

See also VitaminDWiki

See also web

Attached files

ID Name Comment Uploaded Size Downloads
2825 ICU 2011.pdf PDF admin 22 Jul, 2013 04:02 145.53 Kb 1357
See any problem with this page? Report it (WORKS NOV 2021)